A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials.
Spencer S Liu, Wyndam M Strodtbeck, Jeffrey M Richman...
https://pubmed.ncbi.nlm.nih.gov/16301234Actively Recruiting
Phase 4
Age: 8Years - 18Years
All Genders
Healthy Volunteers
ID06590402
A Pilot Study Comparing Anterior Femoral Cutaneous Nerve Blocks to Adductor Canal Blocks in Pediatric Ambulatory Knee Surgeries
Led by Hospital for Special Surgery, New York · Updated on 2025-10-06
60
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare two types of nerve blocks, the anterior femoral cutaneous nerve block (AFCNB) and the adductor canal block (ACB), in children and adolescents aged 8 to 18 undergoing knee surgeries such as anterior cruciate ligament (ACL) and medial patellofemoral ligament (MPFL) reconstruction. The purpose is to gather preliminary information on postoperative function, opioid use, pain levels, sensory effects, and patient-reported outcomes to help design a larger future study. Participants will be randomly assigned to receive either AFCNB or ACB along with standard pain relief care. Each nerve block uses a combination of bupivacaine (a local anesthetic) and dexamethasone (a corticosteroid), with dosing specific to each block type. The study includes two groups: those undergoing ACL surgery and those undergoing MPFL surgery, with 30 subjects total in each group split evenly between the two nerve block types. During the study, participants will keep a daily diary recording pain medication use and pain scores. Follow-up will include surveys and questionnaires administered by phone and during office visits with surgeons. Researchers will assess motor strength, opioid consumption, pain levels at rest and with movement, sensory changes, and patient satisfaction up to six months after surgery. This monitoring aims to understand the effects and recovery outcomes associated with each nerve block technique.
CONDITIONS
Brief Title
Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees
Who Can Participate
Age: 8Years - 18Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- 8-18 years old at the time of surgery
- Weight 40 kg and above
- Scheduled for anterior cruciate ligament (ACL) or medial patellofemoral ligament (MPFL) reconstruction surgery with participating surgeons
You will not qualify if you...
- Revision knee surgery
- Bilateral knee surgery
- Use of general anesthesia
- Contraindications to any part of the study protocol
- Relevant pre-existing neurological deficits
- Chronic pain conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Day of surgery
Participants receive either the anterior femoral cutaneous nerve block (AFCNB) or adductor canal block (ACB) as part of their knee surgery anesthesia and analgesia.
1 visit (in-person surgical procedure)
Post-operative Follow-up
Duration - Up to 6 months post-surgery
Participants maintain a diary to document daily pain medication use and pain scores, and complete follow-up surveys and questionnaires during office visits and telephone calls.
Multiple visits including office visits and telephone follow-ups at 2 weeks, 6 weeks, 3 months, and 6 months post-surgery
Trial Site Locations
Total: 1 location
1
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
Loading map...
Research Team
M
Marko Popovic
A
Alex Sideris, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Bibliometric and Visual Analysis of the Current Status and Trends of Postoperative Pain in Children from 1950-2021.
Cong Wang, Li-Dan Liu, Xue Bai
https://pubmed.ncbi.nlm.nih.gov/36267350Review of outcomes in pediatric patients undergoing anterior cruciate ligament repairs with regional nerve blocks.
Rosella A Micalizzi, Lee Ann Williams, Shelly Pignataro...
https://pubmed.ncbi.nlm.nih.gov/25089833Complications in Pediatric Regional Anesthesia: An Analysis of More than 100,000 Blocks from the Pediatric Regional Anesthesia Network.
Benjamin J Walker, Justin B Long, Madhankumar Sathyamoorthy...
https://pubmed.ncbi.nlm.nih.gov/30074928Quadriceps Weakness After Single-Shot Adductor Canal Block: A Multivariate Analysis of 1,083 Primary Total Knee Arthroplasties.
Elliott J Yee, Zachary A Gapinski, Mary Ziemba-Davis...
https://pubmed.ncbi.nlm.nih.gov/33079899The comparison of adductor canal block with femoral nerve block following total knee arthroplasty: a systematic review with meta-analysis.
Xing-Qi Zhao, Nan Jiang, Fei-Fei Yuan...
https://pubmed.ncbi.nlm.nih.gov/27262287Is Adductor Canal Block Better Than Femoral Nerve Block in Primary Total Knee Arthroplasty? A GRADE Analysis of the Evidence Through a Systematic Review and Meta-Analysis.
Ming-Jie Kuang, Jian-Xiong Ma, Lin Fu...
https://pubmed.ncbi.nlm.nih.gov/28606458Analgesic Efficacy of Adductor Canal Block in Total Knee Arthroplasty: A Meta-analysis and Systematic Review.
Xu Jiang, Qian-Qian Wang, Cheng-Ai Wu...
https://pubmed.ncbi.nlm.nih.gov/27627711Pain Management for Ambulatory Arthroscopic Anterior Cruciate Ligament Reconstruction: Evidence-Based Recommendations From the Society for Ambulatory Anesthesia.
Faraj W Abdallah, Richard Brull, Girish P Joshi...
https://pubmed.ncbi.nlm.nih.gov/30649069Adductor Canal Block Provides Noninferior Analgesia and Superior Quadriceps Strength Compared with Femoral Nerve Block in Anterior Cruciate Ligament Reconstruction.
Faraj W Abdallah, Daniel B Whelan, Vincent W Chan...
https://pubmed.ncbi.nlm.nih.gov/26938989