Actively Recruiting

Phase Not Applicable
Age: 50Years - 80Years
All Genders
ID05556759

Anterior Iliopsoas Muscle Space Block Versus Supra-Iliac Anterior Quadratus Lumborum Block for Analgesia in Total Hip Arthroplasty: A Randomized Controlled Trial

Led by Zagazig University · Updated on 2025-07-15

72

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating two different ultrasound-guided nerve block techniques to manage pain in patients undergoing total hip arthroplasty (THA), a common surgery for hip fractures and osteoarthritis. The study compares the anterior iliopsoas muscle space block and the supra-iliac anterior quadratus lumborum block as pre-emptive analgesia during general anesthesia. Effective pain control is crucial to improve recovery, reduce hospital stay, and support early mobilization after surgery. Participants will be randomly assigned to one of three groups: a control group receiving general anesthesia alone, a group receiving the anterior iliopsoas muscle space block with 30 ml of bupivacaine 0.25% before general anesthesia, or a group receiving the supra-iliac anterior quadratus lumborum block with the same anesthetic dosage before general anesthesia. These blocks target nerves around the hip joint to reduce postoperative pain. During the study, researchers will assess pain using the Visual Analogue Scale at multiple times up to 24 hours after surgery and measure the total rescue analgesia used in the first 24 hours. Patients will be monitored closely for outcomes related to pain relief and recovery. The study is sponsored by Zagazig University and aims to identify the most effective regional anesthesia technique for THA patients aged 50 to 80 years.

CONDITIONS

Brief Title

Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty

Who Can Participate

Age: 50Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient acceptance
  • Age 50 to 80 years old
  • Body mass index (BMI) 30 kg/m2 or less
  • American Society of Anesthesiologists (ASA) classification I to III
  • Scheduled for elective total hip arthroplasty under general anesthesia
Not Eligible

You will not qualify if you...

  • Allergy to local anesthetic agents used in the study
  • Skin lesion at the needle insertion site
  • Bleeding disorders, sepsis, liver disease, or psychiatric disorders
  • Pre-existing neurological deficit in the lower extremity
  • History of chronic pain and use of analgesics
  • History of cognitive dysfunction or mental illness

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Day of surgery

Participants receive either an ultrasound-guided anterior iliopsoas muscle space (IPS) block, a supra-iliac anterior quadratus lumborum (QL) block, or general anesthesia alone as part of their total hip arthroplasty surgery.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - 24 hours post-surgery

Participants are monitored for pain levels and use of rescue analgesia during the first 24 hours after surgery.

Multiple assessments within 24 hours postoperatively

Trial Site Locations

Total: 1 location

1

Faculty of medicine, zagazig university

Zagazig, Alsharqia, Egypt, 4115

Actively Recruiting

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Research Team

S

Shereen E Abd Ellatif, MD

N

Naglaa F Abdelhaleem, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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Published Research Related To This Trial

Ultrasound-guided anterior iliopsoas muscle space block versus posterior lumbar plexus block in hip surgery in the elderly: A randomised controlled trial.

Jing Dong, Yu Zhang, Xiaoxiao Chen...

https://pubmed.ncbi.nlm.nih.gov/33492871