Comparing Front and Back Surgery Approaches for Treating Lumbar Isthmic Spondylolisthesis in Adults

What this Trial Is About

Researchers are studying different surgical methods for treating patients with symptomatic lumbar isthmic spondylolisthesis, a condition affecting the spine. The study compares anterior and posterior interbody fusion surgeries to determine which technique helps reduce leg pain the most. This research is important because doctors do not yet agree on the best surgical approach for this condition, and the study aims to clarify outcomes over time. The study involves two groups of patients who will receive either anterior or oblique interbody fusion surgery with various fixation methods, or posterior interbody fusion surgery using different surgical approaches. These surgeries involve placing devices like synthetic cages or bone grafts to stabilize the spine. The study will collect data over multiple years to assess the results of these surgical options. Participants will be monitored through regular follow-up visits at 1, 2, 5, and 10 years after surgery. Researchers will measure leg pain improvement using a numeric rating scale and track adverse events, reoperations, spinal alignment changes, and quality of life outcomes. The study also includes economic analyses to understand costs related to the surgeries and their effects on patient health and function.

Anterior vs Posterior Surgery for Lumbar Isthmic Spondylolisthesis