Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06823570

Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.

Led by Heinrich-Heine University, Duesseldorf · Updated on 2025-03-12

60

Participants Needed

1

Research Sites

195 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.

CONDITIONS

Official Title

Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Systolic hypertension grade I-II (blood pressure >140 mmHg to <180 mmHg) without previous anti-hypertensive medication treatment
Not Eligible

You will not qualify if you...

  • No written informed consent
  • Age under 18 years
  • Isolated diastolic hypertension
  • Medical reasons preventing exercise treatment such as orthopedic problems or abnormal ECG during exercise test
  • Chronic eye diseases in both eyes, such as macular degeneration or glaucoma, or high intraocular pressure (>20 mmHg)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitätsklinik Düsseldorf

Düsseldorf, Düsseldorf, Germany, 40225

Actively Recruiting

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Research Team

J

Johannes Stegbauer, Prof. Dr.

CONTACT

L

Lukas Streese, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension. | DecenTrialz