Effect of a Gluten-Free, Low-Histamine Diet With or Without Physical Therapy on Plaque Psoriasis in Children Ages 6 to 17

What this Trial Is About

Researchers are studying whether a gluten-free, low-histamine anti-inflammatory diet, with or without added physical therapy, can help children aged 6 to 17 with mild to moderate plaque psoriasis. The study aims to see if these interventions improve skin condition and reduce inflammation. It is a controlled trial with three groups to compare usual care, diet alone, and diet plus exercise over 12 weeks. Participants are randomly assigned to one of three groups continuing standard skin care, following the special diet, or following the diet plus attending supervised physical therapy sessions three times a week. The diet eliminates gluten and high-histamine foods and encourages fruits, vegetables, and healthy fish. The physical therapy includes light aerobic exercise, stretching, and relaxation activities led by a pediatric therapist. Children will have clinic visits at the start, mid-point 6 weeks, and end 12 weeks of the treatment period to assess progress. Researchers will measure psoriasis severity, inflammation markers, quality of life, exercise capacity, body mass index, dietary adherence, and physical therapy attendance. The total participation time is 14 weeks including screening. Safety and treatment effects will be carefully monitored throughout.

Anti Inflammatory Diet With Physical Therapy on Psoriasis