Actively Recruiting
Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy
Led by Recep Tayyip Erdogan University Training and Research Hospital · Updated on 2025-12-17
100
Participants Needed
1
Research Sites
18 weeks
Total Duration
On this page
Sponsors
R
Recep Tayyip Erdogan University Training and Research Hospital
Lead Sponsor
R
Recep Tayyip Erdogan University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aimed to determine the effect of anti-inflammatory nutrition on non-surgical periodontal treatment in individuals with periodontitis by evaluating gingival crevicular fluid (GCF) and serum biomarkers and clinical periodontal parameters. A total of 100 volunteers identified as having a pro-inflammatory diet (Q3 and Q4) will be included in the study. Individuals will be assigned to two groups. These groups will then be further divided into two groups based on whether or not they will receive anti-inflammatory nutrition education. Group Q3-1 (n=25) will receive non-surgical periodontal treatment and anti-inflammatory nutrition education. Group Q3-2 (n=25) will receive only non-surgical periodontal treatment. Group Q4-1 (n=25) will receive non-surgical periodontal treatment and anti-inflammatory nutrition education. Group Q4-2 (n=25) will receive only non-surgical periodontal treatment. After the periodontal index measurements are completed, the patients will receive non-surgical periodontal treatment. GCF and serum samples, periodontal clinical parameters and Dietary Inflammatory Index will be collected 3 times: at baseline, 1.5 and 3 months after non-surgical periodontal treatment. Levels of interleukin (IL)-1β, IL-10, tumor necrosis factor (TNF)-α, total oxidant status (TOS), total antioxidant status (TAS), and C-reactive protein (CRP) will be assessed from these samples. This will investigate the role of anti-inflammatory nutrition in reducing periodontal inflammation and increasing treatment success.
CONDITIONS
Official Title
Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Being systemically healthy
- Not smoking
- Not using anti-inflammatory drugs in the last 3 months
- Not using antibiotics or systemic corticosteroids in the last 6 months
- Not being pregnant or lactating
- Not having received periodontal treatment in the last 6 months
- Having at least 20 teeth in the mouth
- Being diagnosed with periodontitis by the investigator
- Having a dietary inflammatory index greater than 0
You will not qualify if you...
- Having a systemic disease
- Smoking
- Using anti-inflammatory drugs within the last 3 months
- Using antibiotics within the last 6 months
- Using systemic corticosteroids
- Being pregnant or lactating
- Having received periodontal treatment within the last 6 months
- Having fewer than 20 teeth in the mouth
- Not having periodontitis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Recep Tayyip Erdoğan University
Rize, Turkey (Türkiye), 53020
Actively Recruiting
Research Team
H
Hatice Yemenoglu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here