Actively Recruiting

Phase Not Applicable
Age: 6Months - 15Years
All Genders
NCT05575882

Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream for Very Dry, Irritated to Atopic Sensitive Skin.

Led by NAOS Argentina S.A. · Updated on 2025-03-25

100

Participants Needed

3

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Multicentric, double blind, randomized, comparative study with two parallel group: study group vs placebo group. 5 visits: inclusion visit \[day (D) 0\] and 4 follow-up visits (D30, D60, D90, and D120).

CONDITIONS

Official Title

Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream for Very Dry, Irritated to Atopic Sensitive Skin.

Who Can Participate

Age: 6Months - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female between 6 months and 15 years old
  • Moderate atopic dermatitis with an EASI score from 7.1 to 21 on the inclusion day
  • Having on average one flare-up per month during the four months before the study, including the inclusion visit
  • Presence of one atopic skin eruption at inclusion visit prescribed topical corticosteroids or calcineurin inhibitors
  • Healthy except for atopic dermatitis and other atopic diseases such as allergic rhinitis, conjunctivitis, or asthma
  • Able to maintain usual treatments like antihistamines, inhaled corticosteroids, or antileukotriene drugs during the study
  • Written informed consent from parent(s)/legal representative(s) and children over 8 years (Argentina) or over 12 years (Singapore)
  • Willing to continue normal hygiene and sunscreen use if applicable
  • Willingness of participant and parent(s)/legal representative(s) to follow study protocol and procedures
Not Eligible

You will not qualify if you...

  • Presence of other skin conditions in the study area like acne or psoriasis
  • Use of systemic treatments including oral steroids or immunosuppressants in the weeks before the study
  • Use of skin-moisturizing products other than the study product or placebo from inclusion day
  • Systemic therapy with immune-suppressive drugs or antibiotics within 14 days before study start
  • Serious illness requiring regular systemic medication or conditions that could affect study evaluation
  • Documented allergies to ingredients of the study product or placebo
  • Participation in another clinical study during this study period
  • Parent(s)/legal representative(s) considered unlikely to comply with the protocol by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Cirec Latam

Ciudad Autónoma de Buenos Aire, Ciudad Autónoma de Buenos Aire, Argentina, 1426

Not Yet Recruiting

2

CIDP

New Delhi, India, 110005

Actively Recruiting

3

KK Women's & Children's Hospital

Singapore, Singapore, Singapore, 179939

Suspended

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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