Actively Recruiting

Phase 2
Phase 3
Age: 1Month - 12Months
All Genders
NCT00346814

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Led by Asociación para Evitar la Ceguera en México · Updated on 2024-07-31

N/A

Participants Needed

1

Research Sites

904 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Purpose:Retinopathy of prematurity (ROP) continues tobe a major cause of blindness in children. Although ablation of the retina with laser or cryotherapy reduces the incidence of blindness by suppressing the neovascular phase of ROP the visual outcomes after treatment are often poor. Vascular endothelial growth factor(VEGF) has an important role in the pathogenesis of ROP and inhibition of VEGF expression in the neovascular phase might prevent destructive neovascularization in ROP. The aim of this study is to determine the safety and efficacy of intravitreal bevacizumab in the treatment of retinopathy of prematurity

CONDITIONS

Official Title

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Who Can Participate

Age: 1Month - 12Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Retinopathy of prematurity stages III, IV and V where laser or cryotherapy cannot be used
Not Eligible

You will not qualify if you...

  • Patients who can be treated with cryotherapy or laser

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Asociación para Evitar la Ceguera en México Hospital "Luis Sanchez Bulnes"

Mexico City, Mexico DF, Mexico, 04030

Actively Recruiting

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Research Team

H

Hugo Quiroz-Mercado, MD

CONTACT

M

Maria A Martínez-Castellanos, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

0

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Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome | DecenTrialz