Correlations between two plaque indices in assessment of toothbrush effectiveness.
MaryAnn Cugini, Maureen Thompson, Paul R Warren
https://pubmed.ncbi.nlm.nih.gov/17091134Actively Recruiting
Phase Not Applicable
Age: 65Years +
All Genders
Healthy Volunteers
ID06576063
Effects of the Regular Use of Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons Living at Home or at Care Homes
Led by Koite Health Oy · Updated on 2025-08-07
100
Participants Needed
3
Research Sites
26 weeks
Total Duration
On this page
Sponsors
K
Koite Health Oy
Lead Sponsor
U
University of Helsinki
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aging population worldwide is growing rapidly, with more elderly people retaining their natural teeth than before. Maintaining oral health is crucial for older adults, as poor dental condition can lead to complications like infections and reduced quality of life. This research evaluates the use of antibacterial photodynamic therapy (aPDT) combined with antibacterial blue light (aBL) using the Lumoral device, alongside regular dental care, to help improve oral hygiene in elderly people living at home or in care homes. Participants will be divided into two groups: one group will use the Lumoral Treatment device at home combined with standard oral hygiene methods, while the other group will follow only standard oral hygiene practices. The Lumoral device uses a photosensitive mouthwash activated by light to target harmful bacteria in dental plaque. The study will last 9 months, during which participants will receive regular dental appointments and instructions on oral care. Throughout the study, participants will be monitored with dental examinations measuring bleeding on probing, plaque levels, periodontal pocket depth, oral bacterial flora, mouth dryness, and quality of life related to oral health. Safety will be tracked by recording any adverse events. The study aims to assess how the Lumoral Treatment affects oral hygiene, inflammation, and mouth dryness in elderly individuals over this period.
CONDITIONS
Brief Title
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
Who Can Participate
Age: 65Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Age 65 years or older
- Living at home or in a care home with access to regular dental care appointments
- Ability to understand and sign informed consent
- At least 10 teeth in the mouth, including implants
- Ability to understand and follow the study protocol, including tooth brushing and use of the Lumoral Treatment device as assessed by the investigator
You will not qualify if you...
- Uncontrolled diabetes mellitus
- Severe dementia or similar conditions limiting understanding of study information and protocol
- Any physical limitation restricting use of the Lumoral device
- Active smoking or use of other tobacco products
- Antibiotic use within 4 weeks prior to study
- Presence of oral thrush
- Known sensitivity to near-infrared or antibacterial blue light
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 9 months
Participants use standard oral hygiene methods at home. The study group also uses the Lumoral photodynamic antibacterial dual-light device with a marker substance as an adjunctive treatment to improve oral hygiene, reduce inflammation, and alleviate dry mouth.
Regular visits for oral health assessments during the 9-month treatment period
Trial Site Locations
Total: 3 locations
1
SuperSuu
Loviisa, Uusimaa, Finland, 07900
Actively Recruiting
2
SuperSuu
Sipoo, Uusimaa, Finland, 04130
Actively Recruiting
3
KotiHammas
Vantaa, Uusimaa, Finland, 01600
Actively Recruiting
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Research Team
M
Mikko Kylmänen, Master of Health Care
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Repeated Home-Applied Dual-Light Antibacterial Photodynamic Therapy Can Reduce Plaque Burden, Inflammation, and aMMP-8 in Peri-Implant Disease-A Pilot Study.
Hanna Lähteenmäki, Tommi Pätilä, Ismo T Räisänen...
https://pubmed.ncbi.nlm.nih.gov/35723308Indocyanine Green-Assisted and LED-Light-Activated Antibacterial Photodynamic Therapy Reduces Dental Plaque.
Sakari Nikinmaa, Niina Moilanen, Timo Sorsa...
https://pubmed.ncbi.nlm.nih.gov/34063662Changes in Institutionalized Older People's Dentition Status in Helsinki, 2003-2017.
Riitta K T Saarela, Kaija Hiltunen, Päivi Mäntylä...
https://pubmed.ncbi.nlm.nih.gov/31654530Oral hygiene and health-related quality of life in institutionalized older people.
Riitta K T Saarela, Kaija Hiltunen, Hannu Kautiainen...
https://pubmed.ncbi.nlm.nih.gov/34313976Repeated Daily Use of Dual-Light Antibacterial Photodynamic Therapy in Periodontal Disease-A Case Report.
Katherina Trujiilo, Ismo T Räisänen, Timo Sorsa...
https://pubmed.ncbi.nlm.nih.gov/36135158Dental and periodontal health in Finnish adults in 2000 and 2011.
Anna L Suominen, Sinikka Varsio, Sari Helminen...
https://pubmed.ncbi.nlm.nih.gov/29546776