Actively Recruiting
Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients
Led by Centre Hospitalier de Saint-Denis · Updated on 2025-07-04
300
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating different antibiotic treatments for patients in intensive care units who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. The study compares the effects of using one antibiotic (monotherapy) versus a combination of two antibiotics, as well as shorter (7 days) versus longer (14 days) treatment durations. This research also looks at how resistant the bacteria are to antibiotics and how often pneumonia recurs in these patients. The study involves observing patients who meet specific criteria without assigning new treatments directly. It focuses on the antibiotic strategies already being used, comparing their impact on patient survival. The main measurement is survival within 28 days based on the treatment strategy applied. There are no additional experimental interventions since this is an observational study. Participants will be adult patients who were hospitalized in a medical intensive care unit between January 1, 2018, and December 31, 2023, who were intubated and mechanically ventilated with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia. The research team collects data on patient outcomes, antibiotic resistance, and pneumonia recurrence. The study aims to understand which antibiotic approaches may support better survival in this group.
CONDITIONS
Brief Title
Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (age 2518 years)
- Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
- Intubated and mechanically ventilated
- Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia
You will not qualify if you...
- Patients under 18 years old
- Patients who refuse the use of their data for research purposes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 28 days
Participants who undergo routine care are observed to assess patient survival based on antibiotic treatment strategies.
Trial Site Locations
Total: 1 location
1
Centre Hospitalier de Saint-Denis
Saint-Denis, France, France
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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