Actively Recruiting
Population Pharmacokinetics, Effectiveness and Safety of Antiepileptic Drugs in Elderly Patients
Led by Wei Zhao · Updated on 2022-07-15
500
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
Sponsors
W
Wei Zhao
Lead Sponsor
Q
Qianfoshan Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying elderly patients aged 65 to 100 years who have epilepsy to understand how antiepileptic drugs like phenytoin, carbamazepine, lamotrigine, levetiracetam, and perampanel behave in the body. The study aims to evaluate how effective and safe these drugs are in this population and to recommend optimized dosage plans. Participants receive antiepileptic drugs as part of their routine treatment, with the specific drug choice depending on clinical practice. This observational study monitors patients without altering their treatment but collects detailed information on drug levels and effects. During the study, researchers measure drug concentrations at different times after oral administration to track how the medication is processed. They also record any adverse drug reactions and seizure frequency over an average period of 14 days. The study started in 2021 and will continue through June 2028, involving ongoing assessments to better understand treatment outcomes in elderly patients with epilepsy.
CONDITIONS
Brief Title
Antiepileptic Drugs in Elderly Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 years old
- Diagnosed with epilepsy
- Using antiepileptic drugs for treatment
You will not qualify if you...
- Patients who are expected to die within 48 hours
- Patients with allergy to antiepileptic drugs
- Patients receiving other investigational drugs
- Other factors that the researcher considers unsuitable for inclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 14 days
Participants who use antiepileptic drugs as part of routine treatment are observed for drug concentrations and seizure frequency.
Visits occur within 0 to 10 hours after drug administration and at 1 to 2 hours before the next dose, plus monitoring throughout the treatment period
Trial Site Locations
Total: 1 location
1
Wei Zhao
Jinan, Shandong, China
Actively Recruiting
Research Team
W
Wei Zhao
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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