Actively Recruiting
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
Led by Nada Mahmoud Soliman · Updated on 2026-01-05
27
Participants Needed
1
Research Sites
32 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels. The recommended first step is almost always a deep cleaning, which is very effective. However, because some bacteria can hide from cleanings and antibiotics, researchers are exploring a promising light-based treatment. This method uses a safe, light-activated dye and a gentle laser to target and kill bacteria without leading to resistance. To make this treatment even stronger, scientists are testing a way to package the dye inside tiny, biodegradable "containers" that deliver it directly to the germs. The goal of this research is to see if this advanced delivery method works better than the dye alone, hoping to provide a more powerful, non-surgical option to fight gum disease and protect your teeth."
CONDITIONS
Official Title
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both genders aged between 36 and 50 years
- Diagnosed with generalized stage III grade B periodontitis affecting posterior teeth with probing depth over 6 mm and clinical attachment loss of 5 mm or more
- Willing and able to comply with oral hygiene instructions
- Free from systemic diseases that could affect treatment outcomes
You will not qualify if you...
- Current smokers
- Pregnant females
- Drug abusers
- Taken antibiotics or received periodontal treatment in the previous 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry , Ainshams University
Cairo, Egypt, 11566
Actively Recruiting
Research Team
N
Nada Soliman, BDS2017
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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