Actively Recruiting

Phase 2
Phase 3
Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT06207253

The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Led by British University In Egypt · Updated on 2025-05-30

48

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis. The main question\[s\] it aims to answer are: • Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.

CONDITIONS

Official Title

The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with teeth diagnosed with apical periodontitis
  • Periapical Index (PAI) 65 2
  • The teeth are restorable
Not Eligible

You will not qualify if you...

  • Teeth with immature roots
  • Non restorable teeth
  • Medically compromised patients with systemic complication that would alter the treatment
  • Teeth with internal/external root resorption
  • Patient with an allergy to diclofenac sodium

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

British university in Egypt

Cairo, Egypt

Actively Recruiting

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Research Team

S

Summer M Elsayed, Bachelor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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