Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07364565

The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes: A Double Blinded Randomized Controlled Clinical Trial

Led by King Abdullah University Hospital · Updated on 2026-01-23

44

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

K

King Abdullah University Hospital

Lead Sponsor

J

Jordan University of Science and Technology

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating the effects of pure green tea mouthwash on reducing dental plaque and gingival inflammation compared to placebo and essential oils mouthwashes in healthy adults. This double-blinded, randomized, controlled clinical trial aims to determine if pure green tea mouthwash can effectively decrease plaque accumulation and gum inflammation over a three-week period. The study includes healthy participants aged 18 to 50 years with good periodontal health. Participants will be randomly assigned to one of four groups: pure green tea mouthwash, Listerine Total Care mouthwash, Listerine Green Tea mouthwash, or a placebo mouthwash. Each participant will rinse with 10 ml of their assigned mouthwash twice daily for 30 seconds and will avoid all mechanical oral hygiene during the three-week experimental period. Afterward, participants will receive professional cleaning and fluoride treatment and will be followed for two more weeks to ensure oral health recovery. Throughout the study, clinical examinations will be conducted at baseline, and on days 7, 14, and 21 to assess plaque index, gingival index, and staining index. Participants will also report their perception of oral freshness and breath quality. The primary outcome measure is the Turesky modification of the Quigley-Hein plaque index. Safety will be monitored for adverse effects such as gum irritation or sensitivity, with any incidents documented and managed accordingly.

CONDITIONS

Brief Title

The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-smokers
  • Systemically healthy individuals
  • At least 24 teeth in functional dentition, excluding third molars
  • Clinical diagnosis of periodontal health with no pockets over 3 mm, less than 10% bleeding on probing, and no attachment loss
Not Eligible

You will not qualify if you...

  • Smokers
  • Medically compromised patients
  • Pregnant women
  • Allergies to green tea or essential oils
  • Any condition affecting periodontal tissues
  • Presence of any carious lesions
  • Overhang restorations, poorly designed crowns or bridges, or orthodontic retainers
  • Use of systemic antibiotics or anti-inflammatory medications within 3 months prior to enrollment

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 3 weeks

Participants will rinse with 10 ml of their assigned mouthwash twice daily for 30 seconds over a three-week experimental period. During this time, participants will refrain from all forms of mechanical plaque control.

4 visits (baseline, day 7, day 14, and day 21)

Follow-up

Duration - 2 weeks

After the experimental period, participants will receive a professional cleaning and fluoride application and will be followed for two additional weeks to ensure restoration of oral health.

Approximately 1 to 2 visits

Trial Site Locations

Total: 1 location

1

Jordan University of Science and Technology, Faculty of Dentistry

Irbid, Irbid Governorate, Jordan, 22110

Actively Recruiting

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Research Team

L

Lana Bader, DClinDent Perio

D

Dana Adel Abdullah, MClinDent Perio

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Frequently Asked Questions

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