Actively Recruiting

Phase 2
Phase 3
Age: 18Years - 75Years
All Genders
NCT05669820

Antisecretory Factor Glioblastoma Phase 2

Led by Peter Siesjö · Updated on 2026-01-09

300

Participants Needed

1

Research Sites

202 weeks

Total Duration

On this page

Sponsors

P

Peter Siesjö

Lead Sponsor

L

Lund University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a randomised, double blinded and multiple center , Phase 2 study in patients with newly diagnosed glioblastoma. Participants will receive an egg powder enriched for antisecretory factor (AF), Salovum, or a placebo egg powder daily from 2 days before concomitant radio-chemo therapy or chemotherapy until 14 days after finalisation plus during adjuvant chemotherapy.The primary aims of are overall survival at 6 and 12 months after diagnosis

CONDITIONS

Official Title

Antisecretory Factor Glioblastoma Phase 2

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pathology verified glioblastoma or astrocytoma grade 4
  • Age 18-75 years
  • Surgical treatment by resection
  • Scheduled concomitant radiochemotherapy or chemotherapy
  • Provided informed consent
Not Eligible

You will not qualify if you...

  • No informed consent
  • Allergy to egg yolk
  • Only surgical biopsy without resection
  • Receiving only radiotherapy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Skåne University Hospital

Lund, Sweden, 22185

Actively Recruiting

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Research Team

P

Peter Siesjö, MD, PhD

CONTACT

J

Johan Bengzon, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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