The Effects of Antrodia Cinnamomea Fruiting Body Extract on Quality of Life and Chemotherapy Side Effects in Patients With Lung Cancer Undergoing Platinum-Based Chemotherapy

What this Trial Is About

Researchers are evaluating whether a nutritional supplement called Antrodia cinnamomea can improve quality of life for lung cancer patients receiving platinum-based chemotherapy. Lung cancer patients often face side effects like nausea, vomiting, sleep problems, and other symptoms during chemotherapy. This study aims to see if adding Antrodia cinnamomea to turmeric and probiotics can help reduce these side effects and improve overall well-being. Participants will be randomly assigned to one of two groups: one group will take capsules containing Antrodia cinnamomea extract combined with turmeric and probiotics, and the other group will take capsules with turmeric and probiotics only. Both groups will take their assigned capsules orally once daily for 3 months while undergoing chemotherapy. After this, researchers will follow participants for an additional 3 months (up to 24 weeks total) to observe lasting effects of the supplement. During the study, participants will complete questionnaires at multiple timepoints to assess nausea and vomiting, sleep quality, cancer symptoms, and overall quality of life. Researchers will also measure skeletal muscle mass. These assessments will occur at baseline and various weeks during and after treatment. The study is double-blind and randomized, ensuring neither participants nor doctors know which capsules are taken. Total participation lasts about 6 months with regular monitoring.

Antrodia Cinnamomea Extract Effects on Lung Cancer Patients' Quality of Life During Chemotherapy