Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
ID06826417

Pain, Anxiety and Anesthetic Satisfaction for Patients With Different State Anxiety Undergoing Cataract Surgery With Topical Anesthesia

Led by National Taiwan University Hospital · Updated on 2026-04-23

400

Participants Needed

1

Research Sites

15 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating how anxiety traits affect pain, anxiety levels, and satisfaction with anesthesia in patients undergoing cataract surgery using topical anesthesia. The study explores the use of oral anti-anxiety medication, Xanax, compared to a placebo to improve comfort during this common surgery. The aim is to better understand how anxiety and sedation impact the surgical experience and patient satisfaction. Participants will be randomly assigned in a double-blind manner to receive either Xanax or a placebo 30 minutes before their cataract surgery. Anxiety levels will be assessed using the Beck Anxiety Inventory (BAI) and the State-Trait Anxiety Inventory (STAI) questionnaires before and after medication, as well as following surgery. The study focuses on cataract surgery performed with phacoemulsification and intraocular lens implantation under topical anesthesia. During the study, patients will complete anxiety questionnaires at recruitment, before surgery, and after surgery. Pain levels and satisfaction with anesthesia will be measured on the day of surgery and the following day. Researchers will monitor surgical procedures and anesthesia effects closely. The study lasts from recruitment through postoperative follow-up, including assessments up to 1 to 3 months after surgery to analyze anxiety and satisfaction outcomes.

CONDITIONS

Brief Title

Anxiety and Surgery Satisfaction for Cataract Patient With Different State Anxiety

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years old
  • Diagnosed with cataracts
  • Scheduled for cataract surgery with phacoemulsification and intraocular lens implantation under surface anesthesia at National Taiwan University Hospital
  • No adverse reactions to oral anti-anxiety medication (Xanax)
Not Eligible

You will not qualify if you...

  • Any contraindications for surgery before the procedure
  • Any contraindications for medication before the procedure
  • Unable to provide clear and complete answers to relevant questionnaires
  • No preoperative anxiety or scores below 21 on STAI-S or STAI-T assessments
  • Regular use of anti-anxiety medications, sleeping pills, or analgesics before the procedure
  • Pregnancy or breastfeeding during the preoperative period
  • Severe corneal diseases, overripe cataracts, small pupils, or lens dislocation causing surgical difficulties
  • Inability to fully cooperate with the surgical procedure under surface anesthesia
  • Pregnant or uncertain pregnancy status (women under 55 years old to be verbally asked)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Day of surgery

Participants receive either oral Xanax or placebo tablets before cataract surgery under topical anesthesia to assess anxiety and satisfaction.

1 surgery visit (in-person)

Postoperative Follow-up

Duration - 1 day after surgery

Participants are assessed for pain, anxiety, and satisfaction after the cataract surgery.

1 follow-up visit (in-person)

Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan, Taiwan, 100

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Research Team

C

Chiun Ho Hou, Ph.D

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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