Collecting Blood and Other Samples From Children and Adults for Research on Vaccines and Immune Responses

What this Trial Is About

This research aims to collect various human biological samples such as blood, urine, body fluids, skin swabs, and skin biopsies to support medical studies conducted by the National Institute of Allergy and Infectious Diseases Vaccine Research Center. These samples help researchers study diseases including HIV and hepatitis, understand immune responses to infections or vaccinations, and assist in vaccine development. The study is observational and involves volunteers aged 3 years and older. Participants may provide samples through standard blood draws or apheresis, a process that collects larger amounts of blood components by separating them and returning the rest to the body. The apheresis procedure lasts about 1 to 3 hours and is performed with participants resting on a recliner. Depending on the specific research needs, volunteers may donate samples once or multiple times during their enrollment, which lasts for one year and can be extended. Throughout the study, participants will provide specimens that are stored and used for various laboratory research projects related to immunity and vaccine development. Personal information linked to the samples is limited to a participant ID to maintain privacy. The study does not have specific endpoints but focuses on collecting samples safely and according to good clinical practices. Participants may be asked to provide proof of identity and complete informed consent, and their health status will be assessed to ensure safe participation.

Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies