Actively Recruiting
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Led by Wake Forest University Health Sciences · Updated on 2025-12-15
5000
Participants Needed
18
Research Sites
427 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in APOL1 can cause kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks, and Africans are more likely to have the APOL1 gene variants that cause kidney disease. APOLLO will test DNA from kidney donors and recipients of kidney transplants for APOL1 to determine effects on kidney transplant-related outcomes.
CONDITIONS
Official Title
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Living kidney donors with self-reported recent African ancestry (African American, Afro-Caribbean, Hispanic Black, or African)
You will not qualify if you...
- Unable or unwilling to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35233
Actively Recruiting
2
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
3
University of Miami / Miami Transplant Institute
Miami, Florida, United States, 33133
Actively Recruiting
4
Emory University School of Medicine
Atlanta, Georgia, United States, 30322
Actively Recruiting
5
University of Maryland School of Medicine
Baltimore, Maryland, United States, 21201
Actively Recruiting
6
Johns Hopkins University
Baltimore, Maryland, United States, 21205
Actively Recruiting
7
Joslin Diabetes Center / Harvard University
Boston, Massachusetts, United States, 02215
Actively Recruiting
8
University of Michigan Medicine
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
9
Saint Louis University Center for Transplantation
St Louis, Missouri, United States, 63104
Actively Recruiting
10
Ichan School of Medicine at Mount Sinai
New York, New York, United States, 10029
Actively Recruiting
11
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
12
Weill Cornell Medicine
New York, New York, United States, 10065
Actively Recruiting
13
Duke University
Durham, North Carolina, United States, 27705
Actively Recruiting
14
Wake Forest School of Medicine
Winston-Salem, North Carolina, United States, 27157
Actively Recruiting
15
Cleveland Clinic
Cleveland, Ohio, United States, 44106
Actively Recruiting
16
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
17
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
18
University of Wisconsin - Madison
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
L
Laurie P. Russell, MS
CONTACT
B
Benjamin Bagwell, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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