Applicability of a Cellular Level Resolution Full-field OCT Image System for Diagnosis of Pigmented and Non-pigmented Skin Tumors

What this Trial Is About

Skin cancer cases, including both melanoma and non-melanoma types, have been steadily rising over recent decades. This research investigates new imaging technologies to improve the diagnosis of pigmented and non-pigmented skin tumors without needing invasive biopsies. The study evaluates the use of a high-resolution optical coherence tomography (OCT) scanner, the ApolloVueae S100 Image System, which offers detailed skin imaging at the cellular level and combines advantages of existing imaging methods like confocal microscopy and traditional OCT. The study uses the ApolloVueae S100, a CE-certified device that produces two-dimensional, cross-sectional, and en-face images of the skin in real time. This system employs a special light source and camera to create high-speed, high-resolution images, allowing precise examination of skin lesions. Other imaging devices such as confocal microscopy, Vivascopeae, Vivosightae OCT, and dermoscopy with DermLite FotoXae are also used for comparison on a subset of skin lesions. The system's guiding mechanism helps position the probe accurately for detailed scans during the study. Participants with pigmented or non-pigmented skin lesions scheduled for biopsy or excision will undergo imaging assessments using these devices. Researchers will characterize disease features and evaluate diagnostic accuracy over approximately 1.5 years. Data collected includes OCT images, lesion positions, and clinical assessments. This non-invasive imaging study aims to improve skin tumor evaluation while reducing unnecessary biopsies, with no additional treatments given. Participants' progress and skin lesion images will be monitored and recorded throughout the study period.

Applicability of a Cellular Resolution Full-field OCT Image System for Pigmented and Non-pigmented Skin Tumors