Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 80Years
All Genders
NCT06773663

Application of Al18F-NOTA-Pentixafor PET/CT for Primary Aldosteronism

Led by Peking Union Medical College Hospital · Updated on 2025-02-26

150

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This prospective, single-center study investigates the biodistribution, dosimetry, safety, diagnostic performance of Al18F-NOTA-Pentixafor PET imaging in patients with primary aldosteronism. And evaluates the potential of Al18F-NOTA-Pentixafor PET imaging in surgical strategy guidance.

CONDITIONS

Official Title

Application of Al18F-NOTA-Pentixafor PET/CT for Primary Aldosteronism

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with adrenal masses suspected to be aldosterone-producing adenomas based on routine imaging or clinically diagnosed primary aldosteronism patients needing subtyping
  • Signed written informed consent and willingness to follow study procedures
  • Female participants must be surgically sterilized, postmenopausal for over a year, or use reliable contraception
  • Male participants must use reliable contraception during the study and not donate sperm
Not Eligible

You will not qualify if you...

  • Severe neurological disorders or serious diseases affecting major organs or systems
  • Diagnosis of claustrophobia
  • History of drug abuse or alcohol dependence
  • Pregnant or breastfeeding women
  • Poor venous access preventing repeated blood draws
  • Use of experimental drugs or devices within one month prior to the study
  • Any condition posing potential harm or safety concerns as judged by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College

Beijing, China

Actively Recruiting

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Research Team

X

Xinchun Yan, PhD

CONTACT

L

Li Huo, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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