Actively Recruiting
Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-08-20
66
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Evaluation of the effectiveness of Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision compared to local infiltration anesthesia for postoperative analgesia after laparoscopic renal surgery in patients.A randomized controlled trial involving 66 patients undergoing laparoscopic renal surgery will assign them randomly to an experimental group or a control group.The patients in experimental group will receive Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision.The patients in control group will receive local infiltration anesthesia.The primary outcome measure is the cumulative consumption of intravenous morphine equivalents at postoperative 24 hours.The secondary outcomes include the cumulative consumption of intravenous morphine equivalents at postoperative 2, 4, 6, 12 and 48 hours, Numeric Rating Scale(NRS) score at rest and during activity (coughing) at postoperative 2, 6, 24 and 48 hours, Global Comfort Questionnaire(GCQ) Comfort Status Scale Score, Quality of Recovery-15(QoR-15) Postoperative Recovery Scale Score, time of the first press on the Patient-Controlled Analgesia pump, nausea, vomiting, skin itching, drowsiness, or other adverse reactions, regional anesthesia-related complications such as local anesthetic toxicity and length of postoperative hospital stay after surgery.
CONDITIONS
Official Title
Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- ASA physical status I to III
- Scheduled for laparoscopic nephrectomy or partial nephrectomy, including robotic-assisted surgery
You will not qualify if you...
- Recent use of anticoagulants or abnormal blood clotting
- Infection at puncture site, tumors, severe deformities, or systemic infection
- Severe kidney failure (serum creatinine > 442 μmol/L) or liver dysfunction (Child-Pugh Class C)
- Allergy or family history of allergy to local anesthetics
- Preoperative cognitive impairment or inability to assess pain
- Alcoholism, drug abuse, chronic opioid dependence, or use of analgesics/psychotropics over 3 months
- History of nervous system disorders or myasthenia gravis
- Planned intensive care unit admission
- Surgery canceled or patient refusal
AI-Screening
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Trial Site Locations
Total: 1 location
1
Second affiliated Hospital School of Medicine,Zhejiang University
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
L
Lina Yu, doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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