Actively Recruiting
Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery: A Randomized Controlled Trial
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-08-20
66
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of the Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision compared to local infiltration anesthesia for pain relief after laparoscopic renal surgery. This randomized controlled trial involves 66 patients undergoing laparoscopic nephrectomy or partial nephrectomy, with the goal of assessing postoperative analgesia and recovery. The study measures include opioid use, pain scores, comfort, recovery quality, and side effects related to anesthesia. Participants are randomly assigned to one of two groups: the experimental group receives the Anterior Quadratus Lumborum Block using 20 ml of 0.375% ropivacaine hydrochloride administered under laparoscopic direct vision, while the control group receives local infiltration anesthesia with the same dose of ropivacaine. Randomization is done by a clinical researcher using sealed envelopes before surgery. During the study, data collection includes opioid consumption at various postoperative time points up to 48 hours, pain ratings at rest and during activity, comfort and recovery questionnaires, and monitoring for adverse reactions and anesthesia-related complications for up to 72 hours. Length of hospital stay is also recorded for up to 10 days after surgery. Data is carefully recorded in case report forms and maintained in an electronic database, with follow-up assessments to evaluate patient outcomes.
CONDITIONS
Brief Title
Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years old
- American Society of Anesthesiologists physical status classification I to III
- Undergoing laparoscopic nephrectomy or partial nephrectomy including robotic-assisted procedures
You will not qualify if you...
- Recent use of anticoagulants or abnormal blood clotting
- Local infection at puncture site or presence of tumors, severe deformities, or systemic infection
- Severe kidney failure (serum creatinine > 442 bcmol/L or requiring dialysis) or severe liver dysfunction (Child-Pugh Class C)
- Known allergy to local anesthetics or family history of such allergy
- Preoperative cognitive impairment or inability to assess pain
- Alcoholism, drug abuse, chronic opioid dependence, or use of analgesics or psychotropic drugs for more than 3 months
- History of central or peripheral nervous system disorders or myasthenia gravis
- Planned admission to intensive care unit
- Surgical cancellation or patient refusal
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo laparoscopic nephrectomy or partial nephrectomy with either Anterior Quadratus Lumborum Block or local infiltration anesthesia administered during surgery.
1 surgical visit (in-person)
Duration - Up to 10 days after surgery
Participants are monitored for pain levels, comfort, recovery quality, analgesic use, adverse reactions, and complications following surgery.
Visits at 2, 4, 6, 12, 24, 48, and 72 hours post-surgery and assessments up to 10 days
Trial Site Locations
Total: 1 location
1
Second affiliated Hospital School of Medicine,Zhejiang University
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
L
Lina Yu, doctor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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