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Age: 18Years - 65Years
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ID06698718

Using CIELab Spectrophotometry to Measure Gingival Color Changes to Evaluate Basic Periodontal Treatment in Adults with Periodontitis

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-11-21

30

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying the relationship between gum color and clinical signs and inflammatory markers in people with periodontitis. The study plans to include 30 patients diagnosed with periodontitis who visit a hospitals periodontology department between October and November 2024. The goal is to better understand how gum color correlates with inflammation and disease progression. Participants will receive standard periodontal basic treatment. Their age, gender, ethnicity, skin color, and gum type will be recorded. Before treatment and at 6 and 12 weeks afterward, blood tests will measure routine blood counts, high-sensitivity C-reactive protein, and interleukin-6. Samples of gingival fluid will be collected using absorbent paper to assess levels of interleukin-17 and tumor necrosis factor alpha. Clinical measurements including gum color indicators CIE L*, a*, b*, probing depth, bleeding index, and attachment loss will be recorded before treatment and at 2, 6, and 12 weeks after treatment. Participants will undergo multiple assessments across the study period, including blood tests, gum fluid collection, and clinical exams to track changes in gum color and inflammation. The main outcome measured is the change in gum color values 12 weeks after treatment. The study will analyze and compare data before and after treatment to evaluate the effects of periodontal basic therapy. Participation spans about 12 weeks with several follow-up visits to monitor progress and collect samples.

CONDITIONS

Brief Title

Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment

Research Team

S

Sun

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