Actively Recruiting
Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-11-21
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the relationship between gum color and clinical signs and inflammatory markers in people with periodontitis. The study plans to include 30 patients diagnosed with periodontitis who visit a hospital's periodontology department between October and November 2024. The goal is to better understand how gum color correlates with inflammation and disease progression. Participants will receive standard periodontal basic treatment. Their age, gender, ethnicity, skin color, and gum type will be recorded. Before treatment and at 6 and 12 weeks afterward, blood tests will measure routine blood counts, high-sensitivity C-reactive protein, and interleukin-6. Samples of gingival fluid will be collected using absorbent paper to assess levels of interleukin-17 and tumor necrosis factor alpha. Clinical measurements including gum color indicators (CIE L*, a*, b*), probing depth, bleeding index, and attachment loss will be recorded before treatment and at 2, 6, and 12 weeks after treatment. Participants will undergo multiple assessments across the study period, including blood tests, gum fluid collection, and clinical exams to track changes in gum color and inflammation. The main outcome measured is the change in gum color values 12 weeks after treatment. The study will analyze and compare data before and after treatment to evaluate the effects of periodontal basic therapy. Participation spans about 12 weeks with several follow-up visits to monitor progress and collect samples.
CONDITIONS
Brief Title
Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of Han ethnicity, aged between 18 and 65 years old, diagnosed with periodontitis
- No periodontal basic treatment, including scaling, scraping, or flap surgery, in the past six months
- No periodontal surgery or coronal restoration in the anterior teeth area within six months
- Clear thinking, able to communicate well, and high compliance
You will not qualify if you...
- Cardiac function levels III and IV
- Blood pressure higher than 180/110 mmHg
- Pregnant women, women who are pregnant or breastfeeding
- Taking anticoagulants, calcium channel blockers, immunosuppressants, angiotensin drugs, bisphosphonates treatment, or antibiotics within the last 3 months
- Uncontrolled or unstable systemic diseases such as progressive liver disease, infectious diseases, kidney failure, rheumatoid disease, blood disorders, osteoporosis, AIDS, mental illness, or diabetes
- Malignant tumors or undergoing radiotherapy, chemotherapy, or targeted therapy
- Patients with pacemakers who cannot undergo ultrasound therapy
- Current smokers or those who quit less than 5 years ago
- Abnormalities like pigment deposits or keratinized beads on the front teeth or gums
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single treatment session
Participants receive periodontal basic treatment to manage periodontitis.
1 visit (in-person)
Duration - 12 weeks after treatment
Participants undergo CIELab spectrophotometry to analyze gingival color and evaluate treatment effectiveness.
1 follow-up visit
Trial Site Locations
Total: 1 location
1
2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
S
Sun
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here