Actively Recruiting
Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-11-21
30
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Objective: This study aims to explore the correlation between gingival color and clinical indicators and inflammatory factors in patients with periodontitis. Method: This study aims to include 30 periodontitis patients who visited the Periodontology Department of the Second Affiliated Hospital of Zhejiang University School of Medicine from October 2024 to November 2024. The study adopted a self controlled before and after design. All subjects received periodontal basic treatment. Record the age, gender, ethnicity, skin color, and gingival biotype of the subjects. Before treatment, 6 weeks after treatment, and 12 weeks after treatment, check and record the blood routine, high-sensitivity C-reactive protein (Hs CRP), and interleukin-6 (IL-6) of all subjects. Use a moisture absorbing paper tip to collect the gingival crevicular fluid of the subjects, and further detect the levels of interleukin-17 (IL-17) and tumor necrosis factor alpha (TNF - α) in the gingival crevicular fluid samples, and record the periodontal table. Check and record the CIE indicators L \*, a \*, b \*, probing depth (PD), gingival bleeding index (SBI), and clinical attachment loss (CAL) in the keratinized gingival area of all subjects before and after treatment at 2, 6, and 12 weeks. Analyze and compare the changes in each group's data before and after treatment.
CONDITIONS
Official Title
Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of Han ethnicity, aged between 18 and 65 years old, diagnosed with periodontitis
- No periodontal basic treatment, including scaling, scraping, or flap surgery, in the past six months
- No periodontal surgery or coronal restoration in the anterior teeth area within six months
- Clear thinking, able to communicate without obstruction, and high compliance
You will not qualify if you...
- Cardiac function levels III and IV
- Blood pressure higher than 180/110 mmHg
- Pregnant women, women who are pregnant or breastfeeding
- Taking anticoagulants, calcium channel blockers, immunosuppressants, angiotensin medications, bisphosphonates treatment, or antibacterial treatment in the past 3 months
- Uncontrolled or unstable systemic diseases such as progressive liver disease, infectious disease, renal failure, rheumatoid diseases, blood diseases, osteoporosis, AIDS, mental illnesses, or diabetes
- Malignant tumors or undergoing radiotherapy, chemotherapy, or targeted drug therapy
- Having a pacemaker that prevents ultrasound therapy
- Smoking or quit smoking less than 5 years ago
- Abnormalities like pigment deposition or keratinized beads in the front teeth and gums
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
S
Sun
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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