Actively Recruiting
The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU
Led by Peking University Third Hospital · Updated on 2025-02-17
44
Participants Needed
1
Research Sites
115 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to quantitatively assess renal microcirculation changes by contrast-enhanced ultrasound and to obtain systemic hemodynamic information by ultrasound Doppler at the same time, to analyze the relationship between renal microcirculation changes and systemic hemodynamic changes, and to explore its predictive value in renal function recovery in patients with critical acute kidney injury. The main questions it aims to answer are: 1. To explore the quantitative parameters of contrast-enhanced ultrasound which can reflect the changes of renal microcirculation. 2. To explore the relationship between renal microcirculation and systemic hemodynamics. 3. To explore the value of renal microflow changes quantitatively evaluated by contrast-enhanced ultrasound in predicting renal function recovery.
CONDITIONS
Official Title
The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >18 years old
- Acute kidney injury diagnosed less than 24 hours after first admission to intensive care unit (ICU)
- Expected length of stay in ICU at least 48 hours
- Meet Kidney Disease Improving Global Outcomes (KDIGO) 2012 diagnostic criteria for acute kidney injury
- Contrast-enhanced ultrasound performed within 24 hours after AKI diagnosis
You will not qualify if you...
- Known severe chronic kidney disease (stage 4 or higher) or undergoing hemodialysis treatment
- History of kidney transplantation or renal cancer
- Terminal stage of malignant tumor
- Pregnancy
- Renal artery stenosis or renal vein thrombosis
- Allergy to contrast agent SonoVue or its components
- Severe cardiopulmonary insufficiency such as right-to-left shunt heart disease or pulmonary systolic blood pressure over 90 mmHg
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Ultrasound Diagnosis, Peking University Third Hospital
Beijing, Beijing Municipality, China
Actively Recruiting
Research Team
Y
Yuewei Zhang, Dr
CONTACT
L
Ligang Cui, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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