Actively Recruiting
Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children
Led by Children's Hospital of Fudan University · Updated on 2026-02-17
150
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation. Participants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods. Researchers will compare the control group to see whether it can reduce the incidence of ventilator dependence
CONDITIONS
Official Title
Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Stable children receiving mechanical ventilation
- Respiratory rate does not exceed 20% above baseline
- Positive end-expiratory pressure (PEEP) less than 8
- VIS score less than 20
- No hypotension (70 mmHg + age × 2; 70 mmHg if under 1 year old)
- No body temperature over 40°C
- Vital signs not exceeding 95th percentile for age and sex
You will not qualify if you...
- Status epilepticus
- Active intracranial hemorrhage
- Intracranial hypertension
- Unstable fracture of the spine
- Spinal cord injury
- Injuries affecting rehabilitation
- Acute surgery performed on the same day
- Brain function failure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's hospital of Fudan University
Shanghai, Shanghai Municipality, China
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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