Actively Recruiting
Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-05-27
188
Participants Needed
7
Research Sites
13 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead Sponsor
J
Jinhua Municipal Central Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Heat stroke is a serious condition caused by an imbalance between heat production and loss in the body, often triggered by exposure to hot, humid environments or intense exercise. It is characterized by a core body temperature above 40C and brain dysfunction, often leading to damage in multiple organs. The severity depends on the highest temperature reached and how long the body remains overheated. Rapidly lowering body temperature can stop cell damage, reverse organ problems, and improve recovery. However, there is currently no standardized method for emergency teams to manage body temperature effectively in these patients. This study evaluates a new early in-hospital temperature management protocol developed to guide rapid cooling and precise temperature control for heat stroke patients. The protocol includes early detection, selection of cooling methods, target temperature management, and ongoing monitoring. Patients in the experimental group will be treated using this protocol, while data from patients treated with previous standard methods between 2021 and 2022 will be collected retrospectively as a comparison. Participants admitted with heat stroke will be closely monitored for their cooling rate and body temperature within the first 30 minutes and at two hours. Researchers will also track survival rates in the hospital and at three months, along with any complications that arise. The total observation period for outcomes extends to three months, helping evaluate the protocols impact on patient recovery and safety over time.
CONDITIONS
Brief Title
Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted to the emergency department and diagnosed with heat stroke according to the China expert consensus on Heat Stroke
You will not qualify if you...
- Transferred from another hospital and body temperature below 39.5°C
- Discharged within 4 hours with no available subsequent body temperature or outcomes
- Required immediate cardiopulmonary resuscitation
- Had other serious diseases, such as massive cerebral haemorrhage or severe trauma
Research Team
X
Xiuqin Feng
L
lan chen
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