Actively Recruiting

Phase Not Applicable
Age: 2Years - 10Years
All Genders
Healthy Volunteers
NCT06425406

Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

Led by Henan Provincial People's Hospital · Updated on 2025-12-01

48

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.

CONDITIONS

Official Title

Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

Who Can Participate

Age: 2Years - 10Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 2-10 years old
  • American Society of Anesthesiologists (ASA) Level I or II
  • Children with healthy lungs and hearts
  • Clear headed and able to cooperate with anesthesiologists for treatment
Not Eligible

You will not qualify if you...

  • Complete obstruction of the upper respiratory tract
  • Skull base fracture or nasal bone fracture
  • Refusal to use high-flow nasal cannula (HFNC)
  • American Society of Anesthesiologists (ASA) rating greater than Level II
  • Upper respiratory tract infection within 2 weeks
  • Pulmonary dysfunction or congenital heart disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital

Zhengzhou, Henan, China

Actively Recruiting

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Research Team

K

KuangYu Zhao

CONTACT

J

Jun Zhou, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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