Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT07397520

The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years

Led by Instituto de Oftalmología Fundación Conde de Valenciana · Updated on 2026-03-04

30

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine the effectiveness of intralesional 5-fluorouracil in objectively reversing hypertrophic scars in the periocular region resulting from trauma or cosmetic surgery.

CONDITIONS

Official Title

The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female participants aged 18 years
  • Presence of a facial scar in the periocular region secondary to trauma or facial cosmetic surgery
  • Ability and willingness to provide written informed consent
  • Signed informed consent form prior to participation
Not Eligible

You will not qualify if you...

  • Presence of active local infection in the periocular region
  • Active inflammatory dermatologic or ocular disorders in the treatment area
  • Known allergy or hypersensitivity to 5-fluorouracil
  • Pregnancy or breastfeeding
  • Inability to comply with follow-up visits
  • Withdrawal of consent during the study
  • Development of significant local or systemic adverse reactions during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Instituto de Oftalmologia F.A.P. Conde de Valenciana, I.A.P.

Mexico City, Mexico City, Mexico, 06800

Actively Recruiting

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Research Team

D

Diego A Alvarado Herrera MD, Medical Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years | DecenTrialz