Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06551766

The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy

Led by Eye & ENT Hospital of Fudan University · Updated on 2024-08-13

20

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal mucoperiosteal flap, promoting wound healing, forming a good anastomosis, preventing postoperative anastomosis and shortening operation time. Twenty patients with chronic dacryocystitis were randomly divided into photosensitive hydrogel group and suture group.Symptoms and nasal endoscopy were followed up 2, 6, and 12 weeks after surgery for both groups. And also adverse events were recorded at each follow-up.

CONDITIONS

Official Title

The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntarily participate in this clinical study and sign the informed consent
  • Any gender is eligible
  • Age between 18 and 75 years old
  • Patients have symptoms and signs of chronic dacryocystitis with mucous or purulent discharge reflux confirmed by lacrimal passage irrigation
  • Lacrimal duct angiography shows nasolacrimal duct obstruction without canaliculi or duct obstruction
Not Eligible

You will not qualify if you...

  • Age less than 18 or greater than 75 years old
  • Previous history of dacryocystonasal anastomosis
  • Abnormal blood clotting function
  • Tumors in the lacrimal passage, including papilloma or malignant tumors
  • Currently in the acute attack stage of dacryocystitis
  • Known tendency to develop excessive scarring
  • Serious nasal diseases such as severe allergic rhinitis, chronic rhinosinusitis, nasal polyps, acute suppurative rhinosinusitis, severe atrophic rhinitis, or severe nasal septum deviation
  • Serious heart, liver, kidney, lung, or other major diseases preventing general anesthesia
  • Living too far from the hospital to attend postoperative reviews
  • Participation in other clinical trials within the last 3 months
  • Any medical condition that the investigator believes may affect study results or increase risk

AI-Screening

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Trial Site Locations

Total: 1 location

1

Eye & ENT Hospital of Fudan University

Shanghai, China, 200031

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy | DecenTrialz