Using Wide Pulse High Frequency Neuromuscular Electrical Stimulation to Study and Treat Conditions with Motoneuron Overactivity Including Stroke, Muscle Cramps, and Restless Legs Syndrome

What this Trial Is About

Researchers are exploring new ways to study spinal motoneuron overactivity, which can cause problems like muscle cramps, restless legs syndrome, and spasticity after stroke. This project aims to understand these conditions better by using wide pulse high frequency neuromuscular electrical stimulation WPHF NMES as a model. The study also investigates using this stimulation as a training method to improve muscle function in stroke patients. Participants will be divided into two groups one will undergo a 6-week training program using WPHF NMES on the plantar flexor muscles three times a week, while the other group will continue their usual daily activities without intervention. Muscle function will be measured before and after the training period to assess changes. During the study, researchers will evaluate muscle strength, electrical activity, and muscle control using various tests such as maximal voluntary contraction force, NMES-evoked force, and electromyography over an average of 8 weeks. Additional assessments include walking tests and spasticity measures in stroke patients. The study also monitors muscle cramp thresholds and spinal excitability to understand treatment effects and muscle function changes.

The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability