Actively Recruiting
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
Led by Amsterdam UMC, location VUmc · Updated on 2024-05-07
7584
Participants Needed
1
Research Sites
175 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency department with a clinical indication for a blood culture analysis (according to the treating physician). The primary endpoint is 30-day mortality. Key secondary outcomes are: * hospital admission rates * in-hospital mortality * hospital length-of-stay. In the intervention group, the physician will follow the advice of our blood culture prediction tool. In the comparison group all patients will undergo a blood culture analysis.
CONDITIONS
Official Title
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age �30; 18 years
- Have a clinical indication for a blood culture analysis (according to the treating physician)
- Have sufficient data recorded (laboratory results and vital sign measurements) for a prediction to be made (at least 20% of the needed parameters)
You will not qualify if you...
- Central Venous Line (CVL) or Peripherally Inserted Central Catheter (PICC) in situ
- Neutrophil count < 0.5 * 10^9/L
- Candidemia or S. aureus bacteraemia in the past 3 months
- Most likely diagnosis of endocarditis/spondylodiscitis/infected prosthetic material
- Pregnant or breastfeeding patients
- Not capable of giving informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Amsterdam UMC - location AMC
Amsterdam, Netherlands
Actively Recruiting
Research Team
P
Prabath WB Nanayakkara, MD, PhD
CONTACT
S
Sheena C Bhagirath, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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