Actively Recruiting
Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract
Led by Military Institute od Medicine National Research Institute · Updated on 2026-03-10
40
Participants Needed
2
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study will compare proteomic and elemental profiles of aqueous humor and ocular tissues in patients with primary open-angle glaucoma (POAG) and cataract versus cataract controls without glaucoma. Samples collected during standard surgery will be analyzed using LC-MS/MS and ICP-MS. The goal is to identify glaucoma-associated molecular patterns with potential diagnostic or prognostic relevance.
CONDITIONS
Official Title
Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Scheduled for cataract surgery with intraocular lens implantation
- Able to provide written informed consent
- For glaucoma group: diagnosed with primary open-angle glaucoma and cataract, planned combined cataract and glaucoma surgery
- For control group: cataract without glaucoma or other significant eye diseases
You will not qualify if you...
- Under 18 years of age
- Pregnant or breastfeeding
- Severe vision loss in the study eye (worse than counting fingers)
- Any glaucoma type other than primary open-angle glaucoma
- Prior intraocular surgery in the study eye including glaucoma surgery, vitreoretinal surgery, corneal transplant, or refractive surgery
- Active or past uveitis
- Other significant chronic eye diseases in the study eye (except cataract and POAG in glaucoma group)
- Unable to follow study procedures or attend follow-up visits
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Military Institute of Medicine - National Research Institute
Warsaw, Poland
Actively Recruiting
2
University of Warsaw
Warsaw, Poland
Actively Recruiting
Research Team
M
Marek Rękas, MD, PhD
CONTACT
W
Wojciech Mazurek, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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