Actively Recruiting
AR Training Versus Patching in Unilateral Amblyopia
Led by Eye & ENT Hospital of Fudan University · Updated on 2025-04-10
114
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
Sponsors
E
Eye & ENT Hospital of Fudan University
Lead Sponsor
F
First Affiliated Hospital of Fujian Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multi-center, randomized controlled trial to compare the effectiveness of AR training with patching for the treatment of unilateral amblyopia. Specific Aim 1 (Primary): To compare the improvement of visual acuity in the amblyopic eye between AR training and patching for the treatment of unilateral amblyopia. Specific Aim 2 (Secondary): To compare the improvement of visual functions between AR training and patching for the treatment of unilateral amblyopia.
CONDITIONS
Official Title
AR Training Versus Patching in Unilateral Amblyopia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 5 to 55 years (including 5 and 55 years)
- Best-corrected visual acuity worse than 20/30 but no worse than 20/200 in the amblyopic eye
- Interocular difference of 2 or more lines with the better eye within normal range
- Have used optical refractive correction for more than 3 months
- Able to attend visits and complete treatment
- Normal binocular alignment, including strabismic amblyopia with orthotropia after surgical correction, or intermittent exotropia between -15 and 0 prism diopters
You will not qualify if you...
- Organic eye diseases preventing good vision (e.g., ptosis, media opacity, nystagmus, paracentral fixation, acute inflammation, optic nerve or retinal diseases)
- Brain lesions preventing good vision (e.g., cortical visual impairment)
- Implantable electronic device
- History of ocular surgery affecting vision except strabismus surgery
- History of ocular trauma affecting vision
- Receiving amblyopia treatment other than glasses within 2 weeks before study
- History of epilepsy, mental illness, or cognitive defects
- Taking medications that may affect vision during the study
- Unable to comply with treatment or follow-up visits
- Participation in drug clinical trials within 3 months or device trials within 30 days before study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Eye & ENT Hospital of Fudan University
Shanghai, China
Actively Recruiting
Research Team
W
Wen Wen, MD, PhD
CONTACT
Y
Yulian Zhou, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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