Actively Recruiting
ARC-IM Therapy To Support and Promote Recovery of Ambulatory Functions in People With Subacute and Chronic Spinal Cord Injury
Led by Ecole Polytechnique Fédérale de Lausanne · Updated on 2026-04-21
12
Participants Needed
2
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The EIGER study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to support and promote recovery of ambulatory functions, such as walking, in people with subacute and chronic spinal cord injury.
CONDITIONS
Official Title
ARC-IM Therapy To Support and Promote Recovery of Ambulatory Functions in People With Subacute and Chronic Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 65 years old at enrollment
- Have an ASIA Impairment Scale grade of A, B, C, or D
- Have a spinal cord injury level at T10 or higher with intact anatomy extending 6 cm above the conus tip
- Have a traumatic spinal cord injury sustained less than 6 weeks ago (subacute) or more than 1 year ago (chronic)
- Have a stable medical, physical, and psychological condition
- Have residual upper limb function sufficient for weight bearing support
- Be able to understand and communicate in German, French, or English
- Agree to comply with study conditions and attend all appointments
- Provide informed consent before any study procedures
- For women of childbearing potential, have an acceptable or highly effective contraception method
You will not qualify if you...
- Be pregnant or breastfeeding
- Have brain damage
- Have a history of epilepsy
- Have participated in another clinical study with drugs or devices within the past 30 days
- Have previously received stem cell injections in the spinal cord
- Have diseases increasing risks of spinal cord injury surgery
- Require ventilator support
- Have contraindications to mobility (such as unhealed fractures or nervous system disorders)
- Have spinal cord injury from non-traumatic causes (ischemic, tumoral, autoimmune, etc.)
- Have anatomical limitations at the implantation site (e.g., spinal stenosis, bone damage)
- Require an intrathecal baclofen pump
- Have active implanted devices
- Have conditions preventing participation (e.g., renal failure, liver dysfunction, cardiovascular disease)
- Be the investigator, family member, employee, or dependent person of the study team
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Schweizer Paraplegiker-Zentrum (SPZ)
Nottwil, Canton of Lucerne, Switzerland, 6207
Not Yet Recruiting
2
Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
J
Jocelyne Bloch, Prof. Dr. MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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