Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
FEMALE
Healthy Volunteers
NCT07405723

Arm Position and Blood Pressure Measurement Accuracy During Pregnancy

Led by Sheba Medical Center · Updated on 2026-04-16

300

Participants Needed

1

Research Sites

37 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Accurate blood pressure measurement is essential during pregnancy, as blood pressure readings guide clinical decisions related to the diagnosis and management of hypertensive disorders of pregnancy. Clinical guidelines recommend measuring blood pressure with the arm supported at heart level; however, in routine practice, blood pressure is often measured with the arm in non-standard positions. This study aims to evaluate how different arm positions affect blood pressure measurements in pregnant women. Pregnant women attending a high-risk pregnancy clinic will undergo blood pressure measurements with the arm placed in several commonly used positions, including supported at heart level, supported on the lap, and unsupported at the side. Each participant will have multiple measurements taken during a single clinic visit. The study is designed as a randomized crossover trial with stratification by trimester and chronic hypertension status, allowing each participant to serve as her own control. Participants will be enrolled across all three trimesters of pregnancy, and results will be analyzed separately for each trimester. The primary outcome is the difference in systolic and diastolic blood pressure measurements between arm positions. The findings of this study may help improve the accuracy of blood pressure measurement during pregnancy and inform clinical practice regarding optimal measurement techniques.

CONDITIONS

Official Title

Arm Position and Blood Pressure Measurement Accuracy During Pregnancy

Who Can Participate

Age: 18Years - 55Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women aged 18 to 55 years
  • Singleton or multiple viable intrauterine pregnancy
  • Gestational age in the first, second, or third trimester at enrollment
  • Ability to sit upright comfortably during blood pressure measurements
  • Ability to understand study procedures and provide written consent
Not Eligible

You will not qualify if you...

  • Preexisting significant cardiac disease such as arrhythmias, congenital heart disease, or severe valvular disease
  • Chronic kidney disease with serum creatinine 21.5 mg/dL at enrollment
  • Significant upper limb or shoulder conditions affecting arm position or blood pressure measurement, including lymphedema, fractures, prior surgery, or arteriovenous fistula
  • Neurological or musculoskeletal conditions preventing proper positioning
  • Severe preeclampsia, eclampsia, or other acute conditions needing immediate intervention
  • Major fetal anomaly
  • Intrauterine fetal demise

AI-Screening

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Trial Site Locations

Total: 1 location

1

Sheba Medical Center

Ramat Gan, Israel, 5265217

Actively Recruiting

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Research Team

M

Michal Axelrod, MD MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

3

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