Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID07281885
A Randomized Control Trial on the Efficacy of Aromatherapy in Reducing Postoperative Nausea and Vomiting in Total Joint Replacement Patients
Led by Hong Kong Buddhist Hospital · Updated on 2026-01-07
159
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
H
Hong Kong Buddhist Hospital
Lead Sponsor
Q
Queen Elizabeth Hospital, Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of aromatherapy in reducing postoperative nausea and vomiting (PONV) among patients undergoing total joint replacement surgery. This randomized controlled trial involves 159 participants divided into three groups to assess if aromatherapy can improve postoperative care and patient satisfaction as a complementary treatment to standard antiemetic therapies. Participants will be assigned to one of three groups: one receiving aromatherapy patches (lavender-sandalwood or orange-ginger) along with standard care, one receiving placebo patches plus standard care, and a control group receiving only standard prescribed antiemetic treatment. Aromatherapy or placebo patches are applied to the inner side of the patient's top, covered by gauze and micro-pore tape. The intervention and follow-up occur over approximately 24 hours post-surgery. During the study, patients' nausea and vomiting will be measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR) at baseline, 30 minutes after patch application, and at 12 and 24 hours after surgery. Patient satisfaction will also be assessed with a 5-point Likert scale. Data will be analyzed statistically to understand the effects of aromatherapy on PONV and satisfaction, with careful monitoring throughout the study period.
CONDITIONS
Brief Title
Aromatherapy in Reducing PONV for Total Joint Replacement Patients
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Adults aged 18 or above
- Patients scheduled for total joint replacement surgery at the HKBH
You will not qualify if you...
- Cognitive impairments
- Allergy to lavender, orange, ginger, or sandalwood
- Allergy to micro-pore tape
- Allergy to opioid medication
- Undergoing other therapeutic treatment for PONV control, except prescribed medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Approximately 24 hours following surgery
Participants receive standard care for total joint replacement surgery and are randomly assigned to receive either aromatherapy patches, placebo patches, or prescribed antiemetic treatment to reduce postoperative nausea and vomiting.
4 assessments during the first 24 hours post-surgery at specified timepoints: baseline (PACU), 30 minutes after intervention, 12 hours post-intervention, and 24 hours post-intervention
Trial Site Locations
Total: 1 location
1
Hong Kong Buddhist Hospital
Wong Tai Sin, Hong Kong, Hong Kong
Actively Recruiting
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Research Team
C
Choi Wan CHAN, APN (NURSING)
V
Victor CHEUNG, EOII(MDSSC)
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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Published Research Related To This Trial
The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis.
Nathorn Chaiyakunapruk, Nantawarn Kitikannakorn, Surakit Nathisuwan...
https://pubmed.ncbi.nlm.nih.gov/16389016Assessing the psychometric and language equivalency of the Chinese versions of the Index of Nausea, Vomiting and Retching, and the Prenatal Self-Evaluation Questionnaire.
Fan-Hao Chou, Kay C Avant, Shih-Hsien Kuo...
https://pubmed.ncbi.nlm.nih.gov/16089309Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response.
Gabriel Fernando Esteves Cardia, Saulo Euclides Silva-Filho, Expedito Leite Silva...
https://pubmed.ncbi.nlm.nih.gov/29743918Assessing and managing nausea and vomiting in adults.
Claire Ford, Laura J Park
https://pubmed.ncbi.nlm.nih.gov/32516043Clinical and economic burden of postoperative nausea and vomiting: Analysis of existing cost data.
Kyle Gress, Ivan Urits, Omar Viswanath...
https://pubmed.ncbi.nlm.nih.gov/33288118A Pilot Randomized Control Trial to Assess the Impact of Lavender on Anxiety and Comfort After Cesarean Birth and the Barriers Encountered.
https://pubmed.ncbi.nlm.nih.gov/35202019Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies.
Zhaosheng Jin, Tong J Gan, Sergio D Bergese
https://pubmed.ncbi.nlm.nih.gov/33408475Complementary Intervention in Postoperative Care: Aromatherapy's Role in Decreasing Postoperative Nausea and Vomiting.
Emily Marsh, Donna Millette, Alison Wolfe
https://pubmed.ncbi.nlm.nih.gov/34905993Prevalence of postoperative nausea and vomiting: A systematic review and meta-analysis.
Mehrbanoo Amirshahi, Niaz Behnamfar, Mahin Badakhsh...
https://pubmed.ncbi.nlm.nih.gov/31998020