Actively Recruiting
ARON-2 Study-Multicentric International Retrospective Study
Led by Matteo Santoni · Updated on 2025-04-02
367
Participants Needed
1
Research Sites
293 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The ARON-2 study retrospectively analyze patients treated with pembrolizumab as first-line therapy in patients platinum-unfit or as second-line therapy in patients progressed after previous platinum-based chemotherapy. The amendment has been designed to also analyze patients treated with enfortumab vedotin progressed to previous platinum-based chemotherapy and anti-PD-1/PD-L1 inhibitor.
CONDITIONS
Official Title
ARON-2 Study-Multicentric International Retrospective Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged >18 years
- Histologically confirmed diagnosis of urothelial carcinoma of the upper and/or lower urinary tract
- Histologically or radiologically confirmed metastatic disease
- Patients treated with at least one of the following:
- Pembrolizumab in patients progressed after previous platinum-based chemotherapy or as first-line therapy in patients platinum-unfit, with at least 1 cycle between January 1, 2018 and November 30, 2021
- Enfortumab vedotin in patients progressed after previous platinum-based chemotherapy and anti-PD-1/PD-L1 inhibitor, with at least 1 cycle between June 1, 2022 and July 31, 2023
You will not qualify if you...
- Patients without histologically confirmed diagnosis of urothelial carcinoma
- Patients without histologically or radiologically confirmed metastatic disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ospedale di Macerata, UOC Oncologia
Province of Macerata, Macerata, Italy, 62100
Actively Recruiting
Research Team
M
Matteo Santoni, MD, PhD
CONTACT
G
Giulia Sorgentoni
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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