Studying Heart Rhythm and Load During Exercise in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy ARVC

What this Trial Is About

Researchers are investigating arrhythmogenic right ventricular cardiomyopathy ARVC, a condition often affecting young and active individuals, especially those with a history of endurance sports. The study aims to measure and describe the abnormal heart rhythms and cardiac stress that ARVC patients experience during various physical activities within recommended heart rate limits, which currently lack scientific backing. Understanding these effects may help design safer exercise guidelines for these patients. Participants with ARVC will perform several physical activities including treadmill walking, cycling at varied intensities, biceps curls, and loaded squats. Each activity lasts 3 minutes followed by a 10-minute recovery period. Extensive heart monitoring will record the number of premature ventricular beats and cardiac load during these exercises, comparing arrhythmogenic activity across different exercise types. During the study, participants will undergo cardiovascular monitoring to assess heart rhythm disturbances and cardiac load in real time. Researchers will measure premature ventricular beats during activity and recovery, along with cardiac output, blood pressure, and rate-pressure product during exercise. The study includes monitoring medication adherence and compliance with exercise restrictions before testing. Participation involves controlled exercise sessions and heart evaluations, aiming to better understand exercise safety for ARVC patients.

Arrhythmogenic Activity During Exercise in ARVC Patients