Actively Recruiting

Phase 2
Age: 0 - 18Years
All Genders
NCT06088030

Arsenic Trioxide Combined With Chemotherapy for the Treatment of p53-mutated Pediatric Cancer

Led by Yang Li · Updated on 2024-01-03

50

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

Sponsors

Y

Yang Li

Lead Sponsor

R

Ruijin Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This prospective, single-arm, multi-center clinical trial aims to explore and evaluate the efficacy and safety of arsenic trioxide combined with chemotherapy for pediatric cancer with p53 mutation.

CONDITIONS

Official Title

Arsenic Trioxide Combined With Chemotherapy for the Treatment of p53-mutated Pediatric Cancer

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pathological diagnosis of malignant tumor
  • Patient is 18 years old or younger
  • Patient has germline or somatic p53 mutations shown to be partially or completely restored by arsenic trioxide in lab tests
  • Measurable cancer lesions are present
  • Guardian has agreed and signed informed consent
Not Eligible

You will not qualify if you...

  • Patients with one or more critical organ failures such as heart, brain, or kidney failure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China, 510120

Actively Recruiting

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Research Team

Y

Yang Li, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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