Actively Recruiting
ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
Led by University of California, San Diego · Updated on 2024-11-06
500
Participants Needed
5
Research Sites
289 weeks
Total Duration
On this page
Sponsors
U
University of California, San Diego
Lead Sponsor
G
GE Healthcare
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multicenter, multinational trial to evaluate advanced MRI techniques for improved detection of clinically significant prostate cancer (csPCa). The study will enroll 500 participants at 5 clinical centers (100 participants per center). The current standard MRI technique for prostate cancer screening is multiparametric MRI (mpMRI), but two drawbacks include need for intravenous (IV) contrast and dependence on radiologist expertise. The investigators expect that the combination of two other techniques, biparametric MRI (bpMRI) and Restriction Spectrum Imaging restriction score (RSIrs), will help non-expert radiologists achieve similar performance to expert radiologists using bpMRI or mpMRI for detection of csPCa, while avoiding the drawbacks that are present when using mpMRI.
CONDITIONS
Official Title
ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Referred for multiparametric MRI of the prostate due to suspicion of prostate cancer
- MRI performed using the standardized ART-Pro acquisition protocol
You will not qualify if you...
- Currently incarcerated
- Previous diagnosis of prostate cancer
- Active non-prostate tumors near the prostate
- Previous prostate surgery
- History of hip implant
- Metal implants or devices requiring deviation from standard MRI protocol or procedures
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 5 locations
1
University of California San Diego
San Diego, California, United States, 92037
Actively Recruiting
2
University of California, San Francisco
San Francisco, California, United States, 94143
Not Yet Recruiting
3
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Not Yet Recruiting
4
Weill Cornell Medical College
New York, New York, United States, 10065
Not Yet Recruiting
5
Cambridge University Hospitals NHS Foundation Trust
Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ
Not Yet Recruiting
Research Team
T
Tyler Seibert, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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