Sleep and Wake Countermeasures for Artemis: In-laboratory Study

What this Trial Is About

Researchers are studying how different sleep and wake-promoting methods affect the ability to fall asleep quickly, maintain sleep during a nap, and stay alert while awake. The study focuses on testing pink noise during sleep and blue-enriched lighting combined with a nap to see if these interventions improve sleep quality and alertness. This study recruits healthy adults aged 18 to 60 and involves controlled laboratory conditions to minimize bias related to time awareness. Participants will take part in two laboratory visits spaced at least one week apart, after completing a 2-3 week at-home protocol maintaining a regular sleep schedule with at least 8.5 hours in bed each night. They will be randomly assigned to one of three groups: sleep promoting with pink noise plus wake placebo, sleep placebo plus wake promoting with blue-enriched light and a nap, or both sleep promoting and wake promoting. Each participant will experience both an intervention condition and a full placebo condition across the two visits. During each lab visit, participants will be monitored with EEG for sleep stages and quality, and undergo multiple tests including the Karolinska Sleepiness Scale (KSS) for subjective alertness, the psychomotor vigilance task (PVT) for cognitive performance, and saliva sample collection for circadian rhythm markers. Testing occurs hourly except during sleep, and participants will be observed to prevent unplanned sleep. The study includes temperature and vital sign monitoring, provides meals based on preferences, and requires participants not to drive after visits. Total lab time per visit is about 25 hours, with extensive monitoring and evaluation of sleep and alertness outcomes.

Artemis Sleep Countermeasures