Actively Recruiting
The Effect of Upper Extremity Aerobic Exercise Training on Arterial Stiffness in Individuals With Breast Cancer
Led by Hacettepe University · Updated on 2025-12-29
18
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying vascular toxicity caused by anthracyclines and other anticancer drugs, focusing on arterial stiffness in women with breast cancer. The study aims to understand how upper extremity aerobic exercise affects both acute and chronic arterial stiffness responses. This research is important because breast cancer treatments have improved survival but upper limb dysfunction and cardiovascular risks remain concerns that affect quality of life. Participants will take part in a 12-week supervised upper extremity aerobic exercise program, attending three sessions per week, each lasting 25 minutes. The training is designed to evaluate its impact on arterial stiffness and arm exercise capacity. No other treatments or comparison groups are involved in this study. During the study, participants will be monitored for changes in arterial stiffness over one year. Researchers will also assess comorbidities, maximal arm exercise capacity, and cardiovascular disease risk. Participants need to cooperate with tests and complete scales, with regular evaluations to measure how exercise training affects their vascular health and physical function after breast cancer treatment.
CONDITIONS
Brief Title
Arterial Stiffness in Individuals With Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- To be between the ages of 40-69
- Baseline left ventricular ejection fraction (LVEF) greater than 50%
- No coronary artery disease or significant valvular heart disease
- No carotid atherosclerotic plaques
- Volunteering to participate in the research
- At least 15 months after breast cancer surgery
- Able to read and understand scales and cooperate with tests
- Physically inactive, doing less than 60 minutes of structured exercise per week
You will not qualify if you...
- Presence of active infection
- Presence of bilateral breast cancer
- History of surgical, neurological, or orthopaedic problems affecting upper extremity function other than breast cancer surgery
- Neurological disease or other diagnosis affecting cognitive status
- Left ventricular dysfunction or severe liver and kidney dysfunction before chemotherapy
- Musculoskeletal or neurological diseases affecting exercise performance
- Symptomatic heart disease, previous lung surgery, or malignant disease
- Unstable hypertension or diabetes mellitus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 12 weeks
Participants undergo a 12-week supervised upper extremity aerobic exercise training program, with 3 sessions per week lasting 25 minutes each.
3 sessions per week, 25 minutes per session
Trial Site Locations
Total: 1 location
1
Hacettepe University
Ankara, State, Turkey (Türkiye), 06100
Actively Recruiting
Research Team
E
Ebru Calik Kutukcu, PhD
N
Naciye Vardar-Yagli, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here