Study of Arterial Stiffness to Predict Acute Kidney Injury in Adults With Sepsis in Critical Care

What this Trial Is About

Researchers are investigating whether arterial stiffness, measured by Pulse Wave Velocity, can independently predict acute kidney injury in patients with sepsis. The study also compares Pulse Wave Velocity with shear wave ultrasound elastography as different ways to evaluate arterial stiffness in predicting this kidney complication. The research involves collecting detailed patient information including age, sex, medical history, and sepsis source. Clinical data like vital signs, fluid status, and lab tests such as blood counts and kidney function are recorded. Measurements of arterial stiffness using Pulse Wave Velocity and shear wave elastography are taken within the first 24 hours of ICU admission. Renal resistive index is also assessed using Doppler ultrasound. All assessments are done by trained examiners. Participants will be monitored through clinical exams, blood tests, ECG, echocardiography, and sepsis evaluations. Researchers will analyze these data to see how arterial stiffness relates to kidney injury in sepsis over a two-year period. The study tracks organ function scores and collects comprehensive cardiovascular and kidney-related measurements to understand this relationship better.

Arterial Stiffness in Patients With Sepsis