Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT03643926

Arthroscopic Versus Open Brostrom for Ankle Instability

Led by Federal University of São Paulo · Updated on 2024-09-27

98

Participants Needed

2

Research Sites

444 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background: Ankle sprains are among the most prevalent lesions in primary care. A substantial number of these ligament lesions will develop ankle instability and require a surgical procedure. The Brostrom-Gould technique is the standard surgical approach for this condition, providing excellent results over the years. Thru the last decades, the arthroscopic Brostrom has gain popularity and support by several studies. Yet, there is no consensus regarding the best procedure to treat ankle instability nowadays. Hypothesis: The arthroscopic Brostrom technique will present better levels of pain and function when compared to the standard open approach. Design: blinded, in parallel groups, multicentric, randomized, clinical trial. Materials and Methods: 98 patients with a diagnosis of chronic ankle instability, referred from primary or secondary health care services, will be assessed and enrolled in this study. Participants will be divided in two groups (randomized by sequentially numbered identical envelopes, which will be administered serially to participants), one containing the open Brostrom repair technique and the other comprehending the arthroscopic Brostrom approach. The assessments will occur in 3, 6, 12, 24 and 48 weeks. Patients will be evaluated primarily by complications and secondarily the Cumberland Ankle Instability Tool (CAIT), American Orthopedic Foot and Ankle Society (AOFAS), the Visual Analogue Scale (VAS), the Foot Function Index (FFI) and the 36 Item Short Form Health Survey (SF-36). The investigators will use Comparison of Two Proportions via relative frequency analysis, the Pearson Correlation the Chi-Square test and the ANOVA for statistical analyses. Discussion: This study intends to establish if the arthroscopic Brostrom technique can produce excellent and reliable results when treating chronic ankle instability. A shorter surgical time, a better cosmetic appearance and a smaller soft tissue injury would support the choice for this procedure if the outcomes could be compared to the open approach.

CONDITIONS

Official Title

Arthroscopic Versus Open Brostrom for Ankle Instability

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals must be older than 18 and younger than 65 years of age, both genders
  • Participants must have experienced ankle instability symptoms for the last six months
  • Clinical diagnosis of ankle instability with at least one previous ankle sprain and a positive anterior drawer test confirmed by MRI showing lateral ligament injury
Not Eligible

You will not qualify if you...

  • Previous surgery involving the affected foot or ankle
  • History or evidence of autoimmune or peripheral vascular diseases
  • History or evidence of peripheral neuropathy or systemic inflammatory diseases such as rheumatoid arthritis, spondylitis, or Reiter Syndrome
  • Associated injuries like osteochondral lesions, tendon ruptures, or fractures
  • Associated instability such as syndesmotic or medial instability
  • Cavovarus foot deformity
  • BMI over 35
  • Ankle infiltration within six months before initial assessment
  • Pregnancy
  • Any condition contraindicating the proposed therapies
  • Inability to sign the informed consent form
  • History or evidence of blood coagulation disorders (excluding aspirin)
  • Use of a heart pacemaker
  • Presence of infection in the treatment area, either superficial or deep

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Federal University of Minas Gerais

Belo Horizonte, Minas Gerais, Brazil, 31270-901

Not Yet Recruiting

2

Federal University of Sao Paulo

São Paulo, São Paulo, Brazil, 04022-001

Actively Recruiting

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Research Team

N

Nacime SB Mansur, MD

CONTACT

D

Daniel S Baumfeld, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Arthroscopic Versus Open Brostrom for Ankle Instability | DecenTrialz