Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
ID07505485

Artificial Intelligence-Based Assessment of Endosseous Lesions: A Prospective Clinical Study

Led by University of Bari Aldo Moro · Updated on 2026-04-15

10

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial evaluates the use of Artificial Intelligence (AI) to analyze endosseous lesions in patients with maxillary or mandibular cysts. Traditional interpretation of cone beam computed tomography (CBCT) scans relies on qualitative and experience-dependent methods, which may underestimate lesion complexity. The study aims to compare AI-based segmentation and volumetric analysis with conventional CBCT interpretation to assess potential improvements in lesion evaluation and clinical outcomes. Participants will be randomly assigned to either receive conventional CBCT evaluation or AI-assisted evaluation of their scans. The AI tool performs automated segmentation of the lesion, 3D reconstruction, and volumetric calculation to provide objective and reproducible measurements. This approach seeks to enhance surgical planning, predict anatomical involvement, reduce diagnostic errors, and standardize follow-up assessments. During the study, researchers will measure the time required for CBCT interpretation and monitor intraoperative and postoperative complications. Participants will undergo evaluations on day 1, including scan analysis and clinical assessments. The study involves adults aged 18 to 80 years in good health, with no contraindications for surgery, and will continue until May 2026.

CONDITIONS

Brief Title

Artificial Intelligence-Based Assessment of Endosseous Lesions

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Good health according to the System of the American Society of Anesthesiology
  • Aged older than 18 years
  • No general medical contraindication for surgery
Not Eligible

You will not qualify if you...

  • Smoking more than 15 cigarettes a day
  • Pregnancy
  • Acute infections

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Day 1

Participants undergo CBCT scans which are assessed either conventionally or with AI-assisted software for lesion segmentation, 3D reconstruction, and volumetric calculation.

1 visit (in-person)

Trial Site Locations

Total: 2 locations

1

University of Bari Aldo Moro

Bari, Italy, 70021

Actively Recruiting

2

Dr. Giuseppe D'Albis

Bari, Italy, 70124

Actively Recruiting

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Research Team

G

Giuseppe D'Albis, Dr.

S

Saverio Capodiferro, Prof.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

Frequently Asked Questions

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