Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07419048

Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status

Led by University Hospital, Basel, Switzerland · Updated on 2026-02-27

50

Participants Needed

1

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This observational pilot project is to compare AI-guided sonographic IVC measurements with those of human operators (experienced sonographer, beginner sonographer) in two commonly used views (Subcostal (SC)), Right Intercostal (RI)) in healthy, euvolemic participants before and after PLR, which mimics hypervolemia, in order to assess the possible role of AI-guided sonographic IVC measurements by assessing its feasibility and reliability. Each participant will undergo a SC and a RI IVC US assessment before and after PLR by both sonographers, resulting in a total of 8 IVC US examinations with 8 additional AI-guided IVC indices assessments.

CONDITIONS

Official Title

Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy adults aged 18 years or older
  • Approximately 50% biological women
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • History of thrombosis of the inferior vena cava
  • Major cardiovascular event in the last 3 months
  • History of peripheral arterial disease of the legs
  • History of heart failure of any grade
  • History of atrial fibrillation or atrial flutter
  • History of severe valvular disease
  • History of renal failure
  • History of liver cirrhosis
  • History of chronic obstructive lung disease, chronic bronchitis, or pulmonary emphysema
  • History of diabetes mellitus
  • History of arginine-vasopressin disturbance
  • Abdominal surgery within the last 3 months
  • Volume loss due to diarrhea, vomiting, or bleeding within the past 3 days
  • Any respiratory distress
  • Current use of diuretic therapy, ACE inhibitors, or angiotensin receptor blockers
  • Inability to follow procedures or insufficient proficiency in the study language
  • Inability to provide informed consent
  • Vital signs outside normal limits: heart rate over 100 bpm, systolic blood pressure under 85 mmHg, or oxygen saturation below 92%
  • Employees or colleagues directly related to the study team

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University Hospital Basel, Endocrinology, Diabetes and Metabolism

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

L

Laura Potasso, Dr. med. sc.

CONTACT

A

Anna Vital

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status | DecenTrialz