Actively Recruiting

Phase Not Applicable
Age: 22Years +
All Genders
NCT06935591

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

Led by Vektor Medical · Updated on 2026-03-16

423

Participants Needed

13

Research Sites

126 weeks

Total Duration

On this page

Sponsors

V

Vektor Medical

Lead Sponsor

V

Veranex Switzerland SA

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the use of the Vektor Computational ECG Mapping System (vMap®) with pulmonary vein isolation (PVI), to using PVI alone, to treat Atrial Fibrillation (AF) in adults. Participants will have a 50/50 or 1 out of 2 chance of being placed in the treatment or control arm. The control arm of the study involves PVI alone for ablation procedure(s). The treatment arm involves the use of vMap mapping in addition to PVI to plan ablation procedure(s).

CONDITIONS

Official Title

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

Who Can Participate

Age: 22Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with persistent (not longstanding) or recurrent atrial fibrillation
  • Have recent 12-lead electrogram data of atrial fibrillation recorded on approved systems in digital format
  • Medical records confirm atrial fibrillation type, atrial characteristics, prior ablation details
  • At least 22 years old at enrollment
  • Indicated for an ablation procedure by the Investigator
  • Able and willing to comply with study requirements and informed about the study nature
Not Eligible

You will not qualify if you...

  • Arrhythmias other than persistent or recurrent atrial fibrillation, including long-standing persistent AF lasting 1 year or more
  • Unable to obtain acceptable ECG data before or during ablation procedure
  • Participating in another clinical trial with investigational drugs or devices during this study
  • Known or suspected medical conditions posing risk for study participation as judged by Investigator
  • Pregnant at time of enrollment
  • Prior pulmonary vein isolation with all four pulmonary veins confirmed isolated by voltage readings during index procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

Arrhythmia Research Group - St. Bernards

Jonesboro, Arkansas, United States, 72401

Actively Recruiting

2

BayCare Health System

Clearwater, Florida, United States, 33759

Actively Recruiting

3

Baptist Health Jacksonville

Jacksonville, Florida, United States, 32207

Actively Recruiting

4

USF Health

Tampa, Florida, United States, 33606

Actively Recruiting

5

Piedmont Heart of Athens

Athens, Georgia, United States, 30606

Not Yet Recruiting

6

Piedmont Heart Institute

Atlanta, Georgia, United States, 30309

Actively Recruiting

7

Indiana University

Indianapolis, Indiana, United States, 46202

Actively Recruiting

8

Baptist Health Lexignton

Lexington, Kentucky, United States, 40503

Actively Recruiting

9

Westchester Medical Center

Valhalla, New York, United States, 10595

Actively Recruiting

10

OhioHealth

Columbus, Ohio, United States, 43202

Actively Recruiting

11

University of Toledo Medical Center

Toledo, Ohio, United States, 43614

Not Yet Recruiting

12

Penn Presbyterian

Philadelphia, Pennsylvania, United States, 19104-4238

Actively Recruiting

13

German Heart Center

Munich, Germany, 80636

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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