Actively Recruiting
Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-01-23
500
Participants Needed
6
Research Sites
1378 weeks
Total Duration
On this page
Sponsors
M
Memorial Sloan Kettering Cancer Center
Lead Sponsor
M
Montefiore Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to better understand the genetic causes of Hodgkin's disease (a kind of lymphoma) and non-Hodgkin's lymphoma, as well as multiple myeloma, leukemia, and related diseases. The doctors have identified the patient because 1) they have had a lymphoproliferative disorder such as lymphoma, leukemia, or multiple myeloma, and have a family member with one of these disorders or 2) they are a member of a family with a lymphoproliferative disorder, including Hodgkin's disease and/or, non-Hodgkin's lymphoma or a second cancer after Hodgkin's disease.
CONDITIONS
Official Title
Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals with a personal and/or family history of lymphoma, lymphoproliferative B-cell malignancies, or multiple myeloma referred for study participation
- Patients referred from MSKCC outpatient clinics of Lymphoma, Multiple Myeloma, or Leukemia Services in consultation for treatment, identified through history or Family History Questionnaire
- Individuals with relatives or multiple generations affected by Hodgkin's disease, non-Hodgkin's lymphoma, lymphoid leukemia, multiple myeloma, or other lymphoproliferative diseases, prostate or pancreatic cancers, or other hereditary cancer conditions
- Patients with lymphoma associated with colon and renal cancer eligible for DNA storage
- Female patients with Hodgkin's disease who received therapeutic irradiation or developed secondary cancers after Hodgkin's disease
- Family members or probands including siblings, children, grandparents, aunts, and uncles
- Effort to include all living affected and unaffected relatives, especially affected sibling pairs and both parents if alive
- Minors eligible with assent and guardian consent as study involves minimal risk to children
You will not qualify if you...
- N/A
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Commack
Commack, New York, United States, 11725
Actively Recruiting
4
Memorial Sloan Kettering Westchester
Harrison, New York, United States, 10604
Actively Recruiting
5
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Actively Recruiting
6
Memorial Sloan Kettering Rockville
Rockville Centre, New York, United States, 11570
Actively Recruiting
Research Team
K
Kenneth Offit, MD
CONTACT
G
Gilles Salles, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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