Transitioning India to advanced image based adaptive brachytherapy: a national impact analysis of upgrading National Cancer Grid cervix cancer guidelines.
Varsha Hande, Supriya Chopra, Alfredo Polo...
https://pubmed.ncbi.nlm.nih.gov/37694176Actively Recruiting
Led by Tata Memorial Hospital ยท Updated on 2026-02-09
1000
Participants Needed
5
Research Sites
9 weeks
Total Duration
T
Tata Memorial Hospital
Lead Sponsor
C
Chiang Mai University, Thailand
Collaborating Sponsor
Gynecological cancer, particularly cervical cancer, is a significant health challenge in Asia, causing many deaths due to limited preventive care, screening, and cultural delays in seeking treatment. This research focuses on advanced cervical cancer patients treated with radiation and chemotherapy followed by internal radiation called brachytherapy. While advanced brachytherapy methods have shown good results in Western countries, there is a lack of data on their use and outcomes in Asian populations, leading to inconsistent treatment practices. The Asian Gynecological Brachytherapy Registry (ABGR) is a collaborative effort collecting data from multiple centers across Asia. It uses a retrospective cohort design to include patients treated over a 12-month period with different brachytherapy techniques and imaging methods. The registry also gathers information on external radiation, chemotherapy, treatment timing, patient demographics, and treatment planning variations. This comprehensive data aims to understand treatment patterns, outcomes, and factors influencing care across Asian healthcare settings. Participants' medical records will be reviewed to record the types of brachytherapy and radiation treatments used, chemotherapy doses, treatment schedules, and side effects over a three-year period. The study will measure outcomes such as local and regional cancer control, disease-free survival, and radiation-related adverse events. Data quality and patient privacy are maintained through strict protocols, and the findings will support future improvements in cervical cancer care in Asia.
CONDITIONS
Asian Gynecological Brachytherapy Registry in Cervical Cancer
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 years
Participants who have received brachytherapy and concurrent treatments are observed to record treatment patterns, clinical outcomes, and adverse events over time.
Follow-up visits as per routine care
Total: 5 locations
1
Tata Memorial Center
Mumbai, Maharashtra, India, 400012
Actively Recruiting
2
Gunma University
Maebashi, Japan, Japan
Not Yet Recruiting
3
Juntendo University
Tokyo, Japan, Japan
Not Yet Recruiting
4
Mahidol University
Bangkok, Thailand, Thailand
Not Yet Recruiting
5
Chiang Mai University
Chiang Mai, Thailand, Thailand
Not Yet Recruiting
D
Dr. Supriya Chopra
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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