Actively Recruiting
Aspirin for Postpartum Patients With Preeclampsia
Led by MemorialCare Health System · Updated on 2025-06-06
86
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
Sponsors
M
MemorialCare Health System
Lead Sponsor
U
University of California, Irvine
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research study is to evaluate the effect of low-dose aspirin on recovery from severe preeclampsia (a high blood pressure disorder of pregnancy) among women who have given birth. We hypothesize that taking aspirin for the first week after giving birth will enhance recovery from preeclampsia by decreasing the levels of a protein called soluble fms-like tyrosine kinase (sFlt-1), which is thought to be a main contributor to the development of preeclampsia, and speeding up return to a normal blood pressure.
CONDITIONS
Official Title
Aspirin for Postpartum Patients With Preeclampsia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Preeclampsia with severe features diagnosed during delivery admission, as defined by ACOG criteria
- Pre- and postnatal care provided by the Long Beach Memorial Ob/Gyn resident or Maternal-Fetal Medicine clinic
You will not qualify if you...
- Patient age under 18 years old
- Non-English or non-Spanish speaking
- Chronic hypertension diagnosed before 20 weeks' gestation
- Known allergy, prior adverse reaction, or any medical condition where aspirin is contraindicated (nasal polyps, gastric or duodenal ulcers, history of gastrointestinal bleeding, severe liver dysfunction)
- Aspirin prescribed postpartum for any other medical condition
- Bleeding disorder
- Breastfeeding an infant with thrombocytopenia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Miller Children's and Women's Hospital, Long Beach/MemorialCare Long Beach
Long Beach, California, United States, 90740
Actively Recruiting
Research Team
M
Megan C Oakes, MD MSCI
CONTACT
A
Ashten B Waks, MD MSPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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